全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Panagiota N Mitrou , Alison McTaggart
来源:[J].BMC Cancer(IF 3.333), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)The PTEN tumour suppressor gene and PIK3CA proto-oncogene encode proteins which contribute to regulation and propagation of signal transduction through the PI3K/AKT signalling pathway. This study investigates the prevalence of loss of PTEN expression ...
作者:Panagiota N Mitrou , Jennifer Keen ...
来源:[J].The Journal of Pathology(IF 7.585), 2012, Vol.228 (3), pp.405-415Wiley
摘要:Abstract(#br)The tumour suppressor APC is the most commonly altered gene in colorectal cancer (CRC). Genetic and epigenetic alterations of APC may therefore be associated with dietary and lifestyle risk factors for CRC. Analysis of APC mutations in the extended mutation clus...

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