全部文献期刊会议图书|学者科研项目
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作者:Omar S. Usmani , Mathieu Molimard ...
来源:[J].Clinical Pharmacokinetics(IF 6.109), 2017, Vol.56 (10), pp.1139-1154
摘要:In recent years, pathways for the development and approval of bioequivalent inhaled products have been established for regulated markets, including the European Union (EU), and a number of orally inhaled products (OIPs) have been approved in the EU solely on the basis of in ...
作者:... Federico Lavorini , Mark L. Levy , Omar S. Usmani
来源:[J].Drugs & Aging(IF 2.646), 2017, Vol.34 (5), pp.321-330
摘要:Asthma has been demonstrated to be as common in the elderly as in younger age groups. Although no specific recommendations exist to manage the disease differently in older individuals, functional features and clinical presentations may be affected by age per se, and by age-r...
作者:Federico Lavorini , Massimo Pistolesi , Omar S. Usmani
来源:[J].Multidisciplinary Respiratory Medicine(IF 0.151), 2017, Vol.12 (1)
摘要:Pulmonary drug delivery is currently the focus of accelerated research and development because of the potential to produce maximum therapeutic benefit to patients by directly targeting drug to the site of pathology in the lungs. Among the available delivery options, the dry ...
作者:... Andrea Maes , Ubaldo J. Martin , Omar S. Usmani
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018, Vol.111, pp.450-457
摘要:Abstract(#br)This gamma scintigraphy imaging study was the first to assess pulmonary and extrathoracic deposition and regional lung deposition patterns of a radiolabelled long-acting muscarinic antagonist/long-acting β 2 -agonist fixed-dose combination glycopyrronium/formote...
作者:... Nikki Milojevic , Bryan Sheinman , Omar S. Usmani
来源:[J].Pulmonary Pharmacology & Therapeutics(IF 2.543), 2017
摘要:Abstract(#br)This review reflects upon the management of cough in primary, secondary and tertiary care settings. It reviews the burden of cough, the diagnostic tools employed to investigate the cause of cough and pragmatic treatment strategies. A clinical case vignette presenting...
作者:Omar S. Usmani , P.J. Barnes ...
来源:[J].Chest(IF 5.854), 2017, Vol.151 (6), pp.1345-1355
摘要:During the past decade, there has been increasing evidence that the small airways (ie, airways < 2 mm in internal diameter) contribute substantially to the pathophysiologic and clinical expression of asthma and COPD. The increased interest in small airways is, at least in part, a...
作者:Omar S. Usmani , Dave Singh ...
来源:[J].Respiratory Medicine(IF 2.585), 2016, Vol.116, pp.19-27
摘要:Abstract(#br)Background(#br)Small airways dysfunction and inflammation contribute significantly to the clinical impact of asthma, yet conventional methods of assessing airways function in the clinic cannot reliably evaluate its presence. However, most recently, promising met...
作者:... Peter J. Barnes , Omar S. Usmani , Paolo Paredi
来源:[J].Chest(IF 5.854), 2015, Vol.148 (3), pp.731-738
摘要:BACKGROUND(#br)The forced oscillation technique (FOT) measures respiratory resistance and reactance; however, the upper airways may affect the results. We quantified the impact of glottal aperture and buccal air leaks.(#br)METHODS(#br)In the glottal aperture study (1) 10 hea...

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