全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Olga Li , Xiaohong Ma ...
来源:[J].Journal of Neuroimmunology(IF 3.033), 2009, Vol.212 (1), pp.65-73Elsevier
摘要:Abstract(#br)Humanization and modification of the Fc region of anti-human CD3 mAbs have greatly expanded their potential use in chronic T cell mediated diseases. However, low levels of cytokine release and immunogenicity may still impact a chronic dosing strategy. We investi...
作者:Olga Li , Jacqueline McBride ...
来源:[J].PLOS Pathogens(IF 9.127), 2016, Vol.12 (6)PLOS
摘要:Broadly neutralizing antibodies targeting the stalk region of influenza A virus (IAV) hemagglutinin (HA) are effective in blocking virus infection both in vitro and in vivo. The highly conserved epitopes recognized by these antibodies are critical for the membrane fusion function...
作者:Olga Li , Hyunjoo Park
来源:[J].Immunological Investigations(IF 1.731), 2009, Vol.38 (1), pp.76-92Informa Healthcare
摘要:Several low- or non-FcR binding anti-human CD3 monoclonal antibodies have been under investigation for the treatment of autoimmune diseases. To model the mechanism of action of these anti-human CD3 mAbs in the murine system, an Fc-modified anti-mouse CD3 antibody (N297A) was...

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