全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Nienwen Chow , Marwan Sabbagh ...
来源:[J].Neurobiology of Aging(IF 6.166), 2017, Vol.58, pp.225-237Elsevier
摘要:Abstract(#br)The need for a reliable, simple, and inexpensive blood test for Alzheimer's disease (AD) suitable for use in a primary care setting is widely recognized. This has led to a large number of publications describing blood tests for AD, which have, for the most part, not ...
作者:Nienwen Chow , J. H. David Wu
来源:[J].Applied Biochemistry and Biotechnology(IF 1.893), 2015, Vol.175 (2), pp.687-697Springer
摘要:Abstract(#br) Coptotermes formosanus Shiraki is a well-known wood-feeding termite, which can degrade not only cellulose and hemicellulose polysaccharides, but also some aromatic lignin polymers with its enzyme complex to the woody biomass. In this study, a very abundant prot...
作者:Nienwen Chow , Tracy Ali ...
来源:[J].Brain Research(IF 2.879), 2013, Vol.1507, pp.97-104Elsevier
摘要:Abstract(#br)3K3A-APC is a recombinant analog of activated protein C (APC) which is an endogenous protease with multiple functions in the body. Compared to APC, 3K3A-APC has reduced anticoagulant activity but preserved cell signaling activities. In the brain, 3K3A-APC exerts neur...
作者:Janet E Cheetham , Paul D Coleman , Nienwen Chow
来源:[J].Journal of Neuroscience Methods(IF 2.114), 1997, Vol.77 (1), pp.43-48Elsevier
摘要:Abstract(#br)In Alzheimer's disease (AD), one cell in the brain may clearly be affected, while an adjacent cell appears healthy or unaffected. Previous technology has allowed us to examine one message at a time, at the level of a single cell (in situ hybridization, ISH), or multi...
作者:... Tracy Ali , Nienwen Chow , Berislav V. Zlokovic
来源:[J].Brain Research(IF 2.879), 2010, Vol.1347, pp.125-131Elsevier
摘要:Abstract(#br)The anticoagulant activated protein C (APC) protects neurons and vascular cells from injury through its direct cytoprotective effects that are independent of its anticoagulant action. Wild-type recombinant murine APC (wt-APC) exerts significant neuroprotection i...
作者:... Jan Sallstrom , Nienwen Chow , Joseph M. Miano
来源:[J].Brain Pathology(IF 4.739), 2005, Vol.15 (1), pp.78-83Wiley
摘要:According to the prevailing amyloid cascade hypothesis, the onset and progression of a chronic neurodegenerative condition in Alzheimer disease (AD) is initiated by the amyloid β‐peptide (Aβ) accumulation in brain and consequent neuronal toxicity. Recent emphasis on co‐...

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