全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Nels C. Elde , Hopi E. Hoekstra ...
来源:[J].Trends in Ecology & Evolution(IF 15.389), 2019, Vol.34 (9), pp.844-855Elsevier
摘要:Although social behavior can have a strong genetic component, it can also result in selection on genome structure and function, thereby influencing the evolution of the genome itself. Here we explore the bidirectional links between social behavior and genome architecture by consi...
作者:Matthew F. Barber , Nels C. Elde
来源:[J].Trends in Genetics(IF 9.772), 2015, Vol.31 (11), pp.627-636Elsevier
摘要:Host–pathogen interactions provide valuable systems for the study of evolutionary genetics and natural selection. The sequestration of essential iron has emerged as a crucial innate defense system termed nutritional immunity, leading pathogens to evolve mechanisms of ‘iron p...
作者:... Nevan Krogan , Nels C. Elde , Vicente Planelles
来源:[J].Virology(IF 3.367), 2015, Vol.477, pp.10-17Elsevier
摘要:Abstract(#br)Vpr and Vpx are a group of highly related accessory proteins from primate lentiviruses. Despite the high degree of amino acid homology within this group, these proteins can be highly divergent in their functions. In this work, we constructed chimeric and mutant ...
作者:Nels C. Elde , Stephanie J. Child ...
来源:[J].Cell(IF 31.957), 2012, Vol.150 (4), pp.831-841Elsevier
摘要:Summary(#br)In contrast to RNA viruses, double-stranded DNA viruses have low mutation rates yet must still adapt rapidly in response to changing host defenses. To determine mechanisms of adaptation, we subjected the model poxvirus vaccinia to serial propagation in human cell...
作者:Nels C. Elde
来源:[J].Cell Host & Microbe(IF 12.609), 2012, Vol.12 (5), pp.605-606Elsevier
摘要:The high mutation rates of poliovirus and other RNA viruses promote viral diversity by rapid sampling of mutations. In this issue, Lauring et al. (2012) report that underlying synonymous codon variation in virus populations can have a considerable impact on adaptive potential wit...
作者:Nels C. Elde , Manyuan Long , Aaron P. Turkewitz
来源:[J].Trends in Cell Biology(IF 11.721), 2007, Vol.17 (4), pp.157-164Elsevier
摘要:The role of convergent evolution in biological adaptation is increasingly appreciated. Many clear examples have been described at the level of individual proteins and for organismal morphology, and convergent mechanisms have even been invoked to account for similar community stru...
作者:Abdur Rahaman , Nels C. Elde , Aaron P. Turkewitz
来源:[J].Current Biology(IF 9.494), 2008, Vol.18 (16), pp.1227-1233Elsevier
摘要:Summary(#br)Dynamin-related proteins (DRPs) are GTPases that reversibly assemble on cellular membranes[1]. Individual DRPs (here “DRP” includes authentic dynamins) function in fission or tubulation of the plasma membrane, trans-Golgi network, mitochondria, peroxisomes, chlor...

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