全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Naoya Yamashita , Papachan Kolattukudy ...
来源:[J].Brain Research(IF 2.879), 2020, Vol.1736
摘要:Abstract(#br)Proper migration and positioning of Purkinje cells are important for formation of the developing cerebellum. Although several cyclin-dependent kinase 5 (Cdk5) substrates are known to be critical for ordered neuronal migration, there are no reports of mutant mouse-bas...
作者:Shinji Inoue , Naoya Yamashita , Shigeru Yamada
来源:[J].Life Cycle Reliability and Safety Engineering, 2017, Vol.6 (1), pp.15-21
摘要:Multiple regression analysis, where the objective variable represents the number of faults to be detected in the system testing and the software process factors are treated as the explanatory variables, has been widely discussed. However, this approach is unsuitable, because the ...
作者:Naoya Yamashita
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2019, Vol.141 (2), pp.91-96
摘要:Abstract(#br)Neurons extend axons far from cell bodies, and retrograde communications from distal axons to cell bodies and/or dendrites play critical roles in the development and maintenance of neuronal circuits. In neurotrophin signaling, the retrograde axonal transport of ...
作者:Naoya Yamashita , Yuichiro Kanno ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2019, Vol.516 (3), pp.693-698
摘要:Abstract(#br)Triple-negative breast cancer (TNBC) is associated with poor prognosis, because of no effective targeted therapy. In the present study, we demonstrated the crucial role of the aryl hydrocarbon receptor (AhR) in mediating the effects of the chemotherapeutic agent doxo...
作者:Naoya Yamashita , Manami Kondo ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2017, Vol.27 (11), pp.2608-2612
摘要:Abstract(#br)Targeted therapy is unavailable for treating patients with triple-negative breast cancer (TNBC), which accounts for approximately 15% of all breast cancers. Overexpression of epidermal growth factor receptor (EGFR) is observed in approximately 30–60% of TNBCs. T...
作者:Naoya Yamashita , Nao Saito ...
来源:[J].Experimental Cell Research(IF 3.557), 2018, Vol.366 (1), pp.34-40
摘要:Abstract(#br)HER2 overexpression accounts for approximately 15–20% of all breast cancers. We have shown that HER2 overexpression leads to elevated expression of the aryl hydrocarbon receptor (AhR) in breast cancer cells. In this study, firstly, we showed that AhR expression ...
作者:Naoya Yamashita , Yingzhan Tang ...
来源:[J].Bioorganic Chemistry(IF 1.732), 2019, Vol.88
摘要:Abstract(#br)Selective estrogen receptor modulators (SERMs) act as either agonist or antagonist of estrogen receptor (ER) in a tissue selective manner and have been used in several diseases such as breast cancer, postmenopausal syndrome, osteoporosis, and cardiovascular dise...
作者:Naoya Yamashita , Yuko Kawamoto ...
来源:[J].Neurochemistry International(IF 2.659), 2018
摘要:Abstract(#br)CRMP2, alternatively designated as DPYSL2, was the first CRMP family member to be identified as an intracellular molecule mediating the signaling of the axon guidance molecule Semaphorin 3A (Sema3A). In Sema3A signaling, cyclin-dependent kinase 5 (Cdk5) primaril...
作者:Naoya Yamashita , Papachan Kolattukudy ...
来源:[J].Brain Research(IF 2.879), 2017, Vol.1655, pp.161-167
摘要:Abstract(#br)Neural circuit formation is a critical process in brain development. Axon guidance molecules, their receptors, and intracellular mediators are important to establish neural circuits. Collapsin response mediator proteins (CRMPs) are known intercellular mediators ...
作者:Naoya Yamashita , Shuai Zhao ...
来源:[J].Phytomedicine(IF 2.972), 2017, Vol.26, pp.22-27
摘要:Abstract(#br)Background(#br)Pregnane X receptor (PXR) is a key regulator of the induction of drug metabolizing enzymes. PXR has been studied for its importance in drug-drug or herb-drug interactions, and it is also a molecular target for the treatment of inflammatory and met...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×