全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Wolfgang A. Weber , Steven M. Larson , Naga Vara Kishore Pillarsetty
来源:[J].Molecular Imaging and Biology(IF 3.095), 2017, Vol.19 (6), pp.944-951Springer
摘要:We studied the effect of varying specific activity of [68Ga]DKFZ-PSMA11 ([68Ga]DP11) on repeated imaging of prostate-specific membrane antigen-positive (PSMA+) xenograft tumors.
作者:Naga Vara Kishore Pillarsetty , James Russell
来源:[J].EJNMMI Research, 2018, Vol.8 (1), pp.1-4Springer
摘要:Abstract(#br) Background(#br)Quantitative imaging can facilitate patient stratification in clinical trials. The hypoxia-activated prodrug evofosfamide recently failed a phase III trial in pancreatic cancer. However, the study did not attempt to select for patients with hypoxic tu...
作者:Naga Vara Kishore Pillarsetty , Jason A. Konner
来源:[J].EJNMMI Research, 2018, Vol.8 (1), pp.1-10Springer
摘要:Abstract(#br) Background(#br)The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are based on immunohistochemistry. The aim ...
作者:... Blesida Punzalan , Steven M. Larson , Naga Vara Kishore Pillarsetty
来源:[J].Nuclear Medicine and Biology(IF 2.517), 2016, Vol.43 (12), pp.781-787Elsevier
摘要:Abstract(#br)Introduction(#br)Bone marrow is the soft tissue compartment inside the bones made up of hematopoietic cells, adipocytes, stromal cells, phagocytic cells, stem cells, and sinusoids. While [ 18 F]-FLT has been utilized to image proliferative marrow, to date, there...
作者:Naga Vara Kishore Pillarsetty , Jason S. Lewis
来源:[J].Nuclear Medicine and Biology(IF 2.517), 2016, Vol.43 (10), pp.606-611Elsevier
摘要:Abstract(#br)Introduction(#br)Chemokine receptor-4 (CXCR4, fusin, CD184) is expressed on several tissues involved in immune regulation and is upregulated in many diseases including malignant gliomas. A radiolabeled small molecule that readily crosses the blood–brain barrier ...
作者:... Steven M. Larson , Gabriela Chiosis , Naga Vara Kishore Pillarsetty
来源:[J].Journal of Labelled Compounds and Radiopharmaceuticals(IF 1.24), 2016, Vol.59 (3), pp.129-132Wiley
摘要:Heat shock protein 90 (Hsp90) is an ATP dependent molecular chaperone protein whose function is critical for maintaining several key proteins involved in survival and proliferation of cancer cells. PU‐H71 (1), is a potent purine‐scaffold based ATP pocket binding Hsp90 inhibi...
作者:... John L. Humm , Steven M. Larson , Naga Vara Kishore Pillarsetty
来源:[J].PLOS ONE(IF 3.73), 2018, Vol.13 (5)PLOS
摘要:[18F]FAC (2’-deoxy-2’-[18F]fluoro-β-D-arabinofuranosylcytosine, 1 ) is a versatile probe for imaging deoxycytidine kinase (dCK) expression levels in vivo . dCK is responsible for phosphorylation of deoxycytidine (dC, 2 ) and other nucleoside analog...

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