全部文献期刊会议图书|学者科研项目
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作者:Mohammad Ejaz Ahmed , Donovan Tucker ...
来源:[J].Molecular Neurobiology(IF 5.471), 2017, Vol.54 (7), pp.4936-4952Springer
摘要:Caspase-1 is an enzyme implicated in neuroinflammation, a critical component of many diseases that affect neuronal degeneration. However, it is unknown whether a caspase-1 inhibitor can modify apoptotic neuronal damage incurred during transient global cerebral ischemia (GCI)...
作者:Mohammad Ejaz Ahmed , Govindhasamy Pushpavathi Selvakumar ...
来源:[J].Clinical Therapeutics(IF 2.23), 2020
摘要:Abstract(#br)Purpose(#br)Psychological stress is a significant health problem in veterans and their family members. Traumatic brain injury (TBI) and stress lead to the onset, progression, and worsening of several inflammatory and neurodegenerative diseases in veterans and civilia...
作者:Mohammad Ejaz Ahmed , Ramasamy Thangavel ...
来源:[J].Brain Behavior and Immunity(IF 5.612), 2020Elsevier
摘要:Abstract(#br)The molecular mechanism mediating degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease (PD) is not yet fully understood. Previously, we have shown the contribution of glia maturation factor (GMF), a proinflammatory protein in dopaminergic ne...
作者:Mohammad Ejaz Ahmed , Govindhasamy P. Selvakumar ...
来源:[J].Journal of Neuroimmune Pharmacology(IF 3.802), 2019, Vol.14 (7), pp.608-641Springer
摘要:Abstract(#br)Despite significant advancements in the field of molecular neurobiology especially neuroinflammation and neurodegeneration, the highly complex molecular mechanisms underlying neurodegenerative diseases remain elusive. As a result, the development of the next gen...
作者:Mohammad Ejaz Ahmed , Sudhanshu P. Raikwar ...
来源:[J].Journal of Neuroimmune Pharmacology(IF 3.802), 2019, Vol.14 (9), pp.537-550Springer
摘要:Abstract(#br)Microglial cells are brain specific professional phagocytic immune cells that play a crucial role in the inflammation- mediated neurodegeneration especially in Parkinson’s disease (PD) and Alzheimer’s disease. Glia maturation factor (GMF) is a neuroinflammatory ...
作者:Mohammad Ejaz Ahmed , Govindhasamy Pushpavathi Selvakumar ...
来源:[J].Molecular Neurobiology(IF 5.471), 2019, Vol.56 (10), pp.6964-6975Springer
摘要:Abstract(#br)The pathological form of amyloid beta (Aβ) peptide is shown to be toxic to the mitochondria and implicates this organelle in the progression and pathogenesis of Alzheimer’s disease (AD). Mitochondria are dynamic structures constantly undergoing fission and fusio...
作者:Mohammad Ejaz Ahmed , Yan Dong ...
来源:[J].Journal of Molecular Neuroscience(IF 2.891), 2017, Vol.61 (1), pp.42-51Springer
摘要:Abstract(#br)Aberrant calcium influx is a common feature following ischemic reperfusion (I/R) in transient global cerebral ischemia (GCI) and causes delayed neuronal cell death in the CA1 region of the hippocampus. Activation of calcium-calmodulin (CaM)-dependent protein kin...
作者:Mohammad Ejaz Ahmed , Ramasamy Thangavel ...
来源:[J].Molecular Neurobiology(IF 5.471), 2019, Vol.56 (6), pp.3865-3881Springer
摘要:Abstract(#br)Parkinson’s disease (PD) is one of the several neurodegenerative diseases where accumulation of aggregated proteins like α-synuclein occurs. Dysfunction in autophagy leading to this protein build-up and subsequent dopaminergic neurodegeneration may be one of the...
作者:Mohammad Ejaz Ahmed , Harris Zahoor ...
来源:[J].Molecular Neurobiology(IF 5.471), 2018, Vol.55 (9), pp.7132-7152Springer
摘要:Abstract(#br)Parkinson’s disease (PD) is a progressive neurodegenerative disease affecting over five million individuals worldwide. The exact molecular events underlying PD pathogenesis are still not clearly known. Glia maturation factor (GMF), a neuroinflammatory protein in...

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