全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:... Pedro P. Rodríguez-Calvo , Luis Fernández-Vega , Miguel Coca-Prados
来源:[J].BMC Medical Genetics(IF 2.536), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br) LOXL1 gene is the most important genetic risk factor known so far for pseudoexfoliation glaucoma (XFG). Our purpose was to evaluate the potential association of individual genetic variants of the lysyl oxidase-like 1 ( LOXL1 ) gene and haplotype...
作者:... Jesús Ontañón , Miguel Coca-Prados , Julio Escribano
来源:[J].PLoS ONE(IF 3.73), 2019, Vol.13 (12)DOAJ
摘要:Myocilin is an extracellular glycoprotein with a poorly understood biological function and typically known because of its association with glaucoma. In this study, we analyzed the expression and biological activity of human myocilin in some non-ocular tissues. Western immuno...
作者:... Jesús Pintor , Miguel Coca-Prados , Julio Escribano
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (1)DOAJ
摘要:Myocilin is an extracellular glycoprotein of poorly understood function. Mutations of this protein are involved in glaucoma, an optic neuropathy characterized by a progressive and irreversible visual loss and frequently associated with elevated intraocular pressure. We previously...
作者:Miguel Coca-Prados , Sikha Ghosh ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2003, Vol.86 (2), pp.207-216Elsevier
摘要:Abstract(#br)Steroids are potentially important mediators in the pathophysiology of ocular diseases. In this study, we report on the gene expression in the human eye of a group of enzymes, the 17β-hydroxysteroid dehydrogenases (17HSDs), involved in the biosynthesis and inact...
作者:Miguel Coca-Prados , Rosario Pereiro
来源:[J].Talanta(IF 3.498), 2018, Vol.178, pp.222-230Elsevier
摘要:Abstract(#br)The retina contains the highest concentration of zinc in the human eye and it is primarily associated with the retinal pigment epithelium (RPE). Metallothioneins (MTs) are the main cytosolic zinc-ion-binding proteins, exerting a tight control in the number of at...
作者:Miguel Coca-Prados , Janet Davis ...
来源:[J].Graefe's Archive for Clinical and Experimental Ophthalmology(IF 1.932), 1991, Vol.229 (1), pp.84-87Springer
摘要:Abstract(#br)Transforming growth factor-beta (TGF-beta) has recently been found in the aqueous humor. The present study was initiated to test whether the ciliary-body epithelium, the site of aqueous humor formation, is capable of producing TGF-beta. Human, rat and bovine ciliary ...
作者:... Alan G. Palestine , Miguel Coca-Prados , Robert B. Nussenblatt
来源:[J].Graefe's Archive for Clinical and Experimental Ophthalmology(IF 1.932), 2004, Vol.229 (2), pp.191-194Springer
摘要:Abstract(#br)The antigen-specific activation of T-helper lymphocytes is dependent on the presentation of antigen in context with the gene products of the major histocompatibility complex class II (MHC 1I). Aberrant expression of MHC 11 on the ciliary epithelium has been obse...
作者:... José M. Costa-Fernández , Miguel Coca-Prados , Alfredo Sanz-Medel
来源:[J].Analytica Chimica Acta(IF 4.387), 2015, Vol.879, pp.77-84Elsevier
摘要:Abstract(#br)A generic strategy based on the use of CdSe/ZnS Quantum Dots (QDs) as elemental labels for protein quantification, using immunoassays with elemental mass spectrometry (ICP-MS), detection is presented. In this strategy, streptavidin modified QDs (QDs-SA) are bioc...
作者:Miguel Coca-Prados , Julio Escribano , Javier Ortego
来源:[J].Progress in Retinal and Eye Research(IF 9.439), 1999, Vol.18 (3), pp.403-429Elsevier
摘要:Abstract(#br)The generation of expression and subtractive libraries from the ocular ciliary body and cultured ciliary epithelial cells has been instrumental in the cloning, identification and characterization of many genes which, overall reflect a representative profile of t...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×