全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Yuji Ishida , Chise Tateno , Michinori Kohara
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)DOAJ
摘要:Multiple genotype 1a clones have been reported, including the very first hepatitis C virus (HCV) clone called H77. The replication ability of some of these clones has been confirmed in vitro and in vivo, although this ability is somehow compromised. We now report a newly iso...
作者:... Tomohiro Nishimura , Michinori Kohara , Kyoko Tsukiyama-Kohara
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (4)DOAJ
摘要:In our previous study, we demonstrated that 3β-hydroxysterol Δ24-reductase (DHCR24) was overexpressed in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), and that its expression was induced by HCV. Using a monoclonal antibody against DHCR24 (2-152a MAb), we fo...
作者:... Kouichi Morita , Michinori Kohara , Kyoko Tsukiyama-Kohara
来源:[J].Infection, Genetics and Evolution(IF 2.768), 2017, Vol.51, pp.203-210Elsevier
摘要:Abstract(#br)Dengue is an emerging disease of great public health significance worldwide. The lack of a suitable infection model has hampered dengue virus (DENV) pathogenesis study, and developing a suitable small animal model has been a long-standing challenge. The aim of t...
作者:... Yasuhiro Yasutomi , Kyoko Tsukiyama-Kohara , Michinori Kohara
来源:[J].Virology(IF 3.367), 2019Elsevier
摘要:Abstract(#br)Avian-origin influenza viruses like H5N1 and H7N9 often cause severe symptoms with high mortality in humans. Animal models are useful for clarification of the mechanisms of pathogenicity of these infections. In this study, to expand the potential utility of the North...
作者:... Osamu Yoshida , Yoichi Hiasa , Michinori Kohara
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2019, Vol.520 (1), pp.86-92Elsevier
摘要:Abstract(#br)Hepatitis B virus (HBV) infection causes acute and chronic hepatitis, which is a major public health concern worldwide. Immunization methods incorporating hepatitis B surface-small (HBs-S) antigen and hepatitis B core antigen (HBc) have been proposed as candidate the...
作者:Bouchra Kitab , Michinori Kohara , Kyoko Tsukiyama-Kohara
来源:[J].Archives of Virology(IF 2.03), 2018, Vol.163 (7), pp.1717-1726Springer
摘要:Abstract(#br)Dengue is the most prevalent arboviral disease in humans and leads to significant morbidity and socioeconomic burden in tropical and subtropical areas. Dengue is caused by infection with any of the four closely related serotypes of dengue virus (DENV1-4) and usu...

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