全部文献期刊会议图书|学者科研项目
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作者:Michele Malaguarnera , Pietro Pirina
来源:[J].Neurological Sciences(IF 1.412), 2017, Vol.38 (9), pp.1609-1615
摘要:Sardinian (Italy) island population has a uniquely high incidence of amyotrophic lateral sclerosis (ALS). Essential trace element levels in blood, hair, and urine of ALS Sardinian patients were investigated in search of valid biomarkers to recognize and predict ALS. Six elements ...
作者:Michele Malaguarnera , Roberto Madeddu ...
来源:[J].Journal of Medical Case Reports, 2017, Vol.11 (1)
摘要:This case report describes a spontaneous tumor lysis syndrome due to a rare solid tumor.
作者:... Michele Vecchio , Filippo Drago , Michele Malaguarnera
来源:[J].Translational Medicine Communications, 2017, Vol.2 (1)
摘要:The employment status of workers with chronic hepatitis C has important implications for society and labor market, for organizations and for the individuals and their economic, social and psychological status. To evaluate the effects to Peg-IFN-α and RBV treatment on work ab...
作者:Michele Malaguarnera , Marta Llansola
来源:[J].Brain Behavior and Immunity(IF 5.612), 2018, Vol.69, pp.386-398
摘要:Abstract(#br)Hyperammonemia is a main contributor to cognitive impairment and motor in-coordination in patients with hepatic encephalopathy. Hyperammonemia-induced neuroinflammation mediates the neurological alterations in hepatic encephalopathy. Intracerebral administration...
作者:Michele Malaguarnera , Sara Gil-Perotin ...
来源:[J].Journal of Hepatology(IF 9.858), 2019
摘要:Abstract(#br)Background & Aims(#br)Chronic hyperammonemia induces neuroinflammation which mediates cognitive impairment. How hyperammonemia induces neuroinflammation remains unclear. We propose the hypothesis that chronic hyperammonemia would induce peripheral inflammation that w...
作者:Michele Malaguarnera , Ana Agusti
来源:[J].Food and Chemical Toxicology(IF 3.01), 2017, Vol.99, pp.135-148
摘要:Abstract(#br)The use of pesticides has been associated with impaired neurodevelopment in children. The aims of this work were to assess: 1) the effects on spatial learning of developmental exposure to pesticides 2) if the effects are sex-dependent and 3) if hippocampal neuroinfla...
作者:Michele Malaguarnera , Alessandro Giuseppe Fois ...
来源:[J].Chemosphere(IF 3.137), 2018, Vol.197, pp.457-466
摘要:Abstract(#br)An exploratory study of trace elements in ALS and their relationships with clinical severity was detected. Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that causes irreversible damage in humans, with the consequent loss of function of motoneuro...
作者:... Rita Bella , Filippo Drago , Michele Malaguarnera
来源:[J].Nutrients(IF 2.072), 2018, Vol.10 (3)
摘要:Background: Minimal Hepatic Encephalopathy (MHE) is characterized by an impairment of social interaction, emotional behavior, sleep disorders, physical and mental symptoms, and diminished Quality of Life (QoL). The aim of our study is evaluating the potential liver health promoti...
作者:Michele Malaguarnera , Sherry Dadsetan ...
来源:[J].Neurochemistry International(IF 2.659), 2015, Vol.88, pp.15-19
摘要:Abstract(#br)The cognitive and motor alterations in hepatic encephalopathy (HE) are the final result of altered neurotransmission and communication between neurons in neuronal networks and circuits. Different neurotransmitter systems cooperate to modulate cognitive and motor...
作者:Michele Malaguarnera , Lucas Taoro-Gonzalez ...
来源:[J].Scientific Reports(IF 2.927), 2016, Vol.6 (1), pp.1084-1102
摘要:Abstract(#br)It has been proposed that extracellular cGMP modulates the ability to learn a Y maze task, but the underlying mechanisms remained unknown. Here we show that extracellular cGMP, at physiological concentrations, modulates learning in the Y maze in a biphasic way by mod...

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