全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Merete Bjørnslett , Mari Kyllesø Halle ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact ...
作者:Merete Bjørnslett , Leonardo A. Meza-Zepeda ...
来源:[J].Molecular Cancer(IF 5.134), 2017, Vol.16 (1)Springer
摘要:Colorectal cancer (CRC) cell lines are widely used pre-clinical model systems. Comprehensive insights into their molecular characteristics may improve model selection for biomedical studies.
作者:Merete Bjørnslett , Espen Melum ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (7)DOAJ
摘要:The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4-6 are spliced out to encode the shorter CD45R0 in antigen-experienced ef...
作者:Merete Bjørnslett , Alv A. Dahl ...
来源:[J].Familial Cancer(IF 1.935), 2015, Vol.14 (4), pp.495-504Springer
摘要:Abstract(#br)An increasing demand for genetic testing has moved the procedure from highly selected at-risk individuals, now also including cancer patients for treatment associated testing. The heritable fraction of ovarian cancer is more than 10 %, and our department has offered ...
作者:Merete Bjørnslett , Mari Kyllesø Halle ...
来源:[J].Tumor Biology(IF 2.518), 2016, Vol.37 (8), pp.10697-10702Springer
摘要:Abstract(#br)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in several cancer forms. Recently, a single...
作者:Merete Bjørnslett , Mari Kyllesø Halle ...
来源:[J].2017, Vol.17 (1), pp.97BMC
摘要:The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the im...
作者:Merete Bjørnslett , Vincent G.H Eijsink
来源:[J].FEMS Microbiology Letters(IF 2.049), 1998, Vol.168 (1), pp.137-143Elsevier
摘要:Abstract(#br)A system for efficient heterologous expression of class II bacteriocins is described that is based on introducing two plasmids in a bacteriocin-negative Lactobacillus sake strain. The first plasmid (pSAK20) contains the genes necessary for transcriptional activation ...
作者:Merete Bjørnslett , Line M. Myklebust ...
来源:[J].Cancer Cell(IF 24.755), 2010, Vol.19 (2), pp.273-282Elsevier
摘要:Summary(#br)MDM2 plays a key role in modulating p53 function. The MDM2 SNP309T > G promoter polymorphism enhances Sp1 binding and has been linked to cancer risk and young age at diagnosis although with conflicting evidence. We report a second MDM2 promoter polymorphism, SNP2...
作者:Merete Bjørnslett , Stian Knappskog ...
来源:[J].2012, Vol.12 (1), pp.454BMC
摘要:While BRCA mutation carriers possess a 20-40% lifetime risk of developing ovarian cancer, knowledge about genetic modifying factors influencing the phenotypic expression remains obscure. We explored the distribution of the MDM2 polymorphisms SNP309T>G and the recently discovered ...

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