全部文献期刊会议图书|学者科研项目
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作者:Matthew Crowe , Nicole K.H. Yiew ...
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2018
摘要:Abstract(#br)Objective(#br)Inflammation in adipose tissues in obesity promotes insulin resistance and metabolic disease. The Duffy antigen receptor for chemokines (DARC) is a promiscuous non-signaling receptor expressed on erythrocytes and other cell types that modulates tissue i...
作者:Matthew Crowe
来源:[J].Redox Biology, 2015, Vol.5, pp.414-414
摘要:Background(#br)The Ras family of small GTPases cycle between an inactive, GDP-bound state and an active, GTP-bound state. When bound to GTP, Ras engages and activates a number of effectors that mediate proliferative and survival signals. Ras is mutated in over 30% of human cancer...
作者:Matthew Crowe
来源:[J].Redox Biology, 2015, Vol.5 (C)
摘要:The Ras family of small GTPases cycle between an inactive, GDP-bound state and an active, GTP-bound state. When bound to GTP, Ras engages and activates a number of effectors that mediate proliferative and survival signals. Ras is mutated in over 30% of human cancers, usually at c...
作者:Matthew Crowe , Nolwenn Lucas ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2012, Vol.22 (7), pp.2620-2623
摘要:Abstract(#br)A series of novel benzimidazoles are discussed as NR2B-selective N -methyl- d -aspartate (NMDA) receptor antagonists. High throughput screening (HTS) efforts identified a number of potent and selective NR2B antagonists such as 1 . Exploration of the substituents arou...
作者:Matthew Crowe , Drew Robinson ...
来源:[J].Therapeutics and Clinical Risk Management, 2019, Vol.2019 (default), pp.397-403
摘要:Chronic Eosinophilic Pneumonia (CEP) is an eosinophilic lung disease that is typically diagnosed by a triad of clinical symptoms including pulmonary symptoms, eosinophilia and characteristic radiographic abnormalities. It requires a high index of suspicion given its overlap with ...

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