全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Masahiko Takada , Motokazu Uchigashima ...
来源:[J].Brain Structure and Function(IF 7.837), 2017, Vol.222 (5), pp.2359-2378Springer
摘要:In the present study, we generated a novel parvalbumin (PV)-Cre rat model and conducted detailed morphological and electrophysiological investigations of axons from PV neurons in globus pallidus (GP). The GP is considered as a relay nucleus in the indirect pathway of the basal ga...
作者:... Masanori Imamura , Hirohisa Hirai , Masahiko Takada
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (11)DOAJ
摘要:In our institute, we have recently found a child Japanese monkey who is characterized by deep wrinkles of the skin and cataract of bilateral eyes. Numbers of analyses were performed to identify symptoms representing different aspects of aging. In this monkey, the cell cycle of fi...
作者:... Atsushi Nambu , Tomoki Fukai , Masahiko Takada
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.6 (4)DOAJ
摘要:Several areas of the brain are known to participate in temporal processing. Neurons in the prefrontal cortex (PFC) are thought to contribute to perception of time intervals. However, it remains unclear whether the PFC itself can generate time intervals independently of external s...
作者:... Yoshiyuki Kuroiwa , Fumiaki Tanaka , Masahiko Takada
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (11)DOAJ
摘要:In neurodegenerative disorders, such as Parkinson's disease (PD), alpha-synuclein (α-syn) accumulates to induce cell death and/or form a cytoplasmic inclusion called Lewy body (LB). This α-syn-related pathology is termed synucleinopathy. It remains unclear how α-syn accumula...
作者:... Hiromasa Sawamura , Ken-Ichi Inoue , Masahiko Takada
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (12)DOAJ
摘要:Retrograde transsynaptic transport of rabies virus was employed to undertake the top-down projections from the medial temporal lobe (MTL) to visual area V4 of the occipitotemporal visual pathway in Japanese monkeys (Macaca fuscata). On day 3 after rabies injections into V4, neuro...
作者:... Shigeki Kato , Kazuto Kobayashi , Masahiko Takada
来源:[J].Neuroscience Research(IF 2.204), 2017Elsevier
摘要:Abstract(#br)Lentiviral vectors have been used not only for various basic research experiments, but also for a wide range of gene therapy trials in animal models. The development of a pseudotyped lentiviral vector with the property of retrograde infection allows us to introduce f...
作者:... Ken-ichi Inoue , Masahiko Takada , Kazuto Kobayashi
来源:[J].Journal of Neuroscience Methods(IF 2.114), 2018Elsevier
摘要:Abstract(#br)Background(#br)Pseudotyping of a lentiviral vector with fusion glycoproteins composed of rabies virus glycoprotein (RVG) and vesicular stomatitis virus glycoprotein (VSVG) segments achieves high gene transfer efficiency through retrograde transport in the nervou...
作者:... Masafumi Nejime , Masahiko Takada , Masayuki Matsumoto
来源:[J].Neuron(IF 15.766), 2018, Vol.100 (6), pp.1513-1526.e4Elsevier
摘要:Summary(#br)Animals need to inhibit inappropriate actions that would lead to unwanted outcomes. Although this ability, called response inhibition, is impaired in neurological/psychiatric disorders with dopaminergic dysfunctions, how dopamine regulates response inhibition remains ...

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