全部文献期刊会议图书|学者科研项目
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作者:... B.A. Wallace , Oscar Ces , Martin Buck
来源:[J].BBA - Biomembranes(IF 3.389), 2017, Vol.1859 (1), pp.28-39
摘要:Abstract(#br)The phage shock protein (Psp) response maintains integrity of the inner membrane (IM) in response to extracytoplasmic stress conditions and is widely distributed amongst enterobacteria. Its central component PspA, a member of the IM30 peripheral membrane protein fami...
作者:... Nan Zhang , Martin Buck , Xiaodong Zhang
来源:[J].Molecular Cell(IF 15.28), 2017, Vol.67 (1), pp.106-116.e4
摘要:Summary(#br)Gene transcription is carried out by RNA polymerases (RNAPs). For transcription to occur, the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter complex (RPo), where the DNA is melted out into a transcription bubble ...
作者:... Mark H. Bennett , Martin Buck , Mauricio Barahona
来源:[J].Biophysical Journal(IF 3.668), 2017, Vol.112 (10), pp.2219-2230
摘要:Abstract(#br)Ammonium assimilation in Escherichia coli is regulated by two paralogous proteins (GlnB and GlnK), which orchestrate interactions with regulators of gene expression, transport proteins, and metabolic pathways. Yet how they conjointly modulate the activity of glutamin...
作者:Martin Buck , Robert J. Kuether ...
来源:[J].Mechanical Systems and Signal Processing(IF 1.913), 2019, Vol.114, pp.579-603
摘要:Abstract(#br)The Hurty/Craig-Bampton method in structural dynamics represents the interior dynamics of each subcomponent in a substructured system with a truncated set of normal modes and retains all of the physical degrees of freedom at the substructure interfaces. This makes th...
作者:... Milija Jovanovic , Martin Buck , Xiaodong Zhang
来源:[J].Journal of Molecular Biology(IF 3.905), 2019, Vol.431 (20), pp.3960-3974
摘要:Abstract(#br)Cellular RNA polymerase is a multi-subunit macromolecular assembly responsible for gene transcription, a highly regulated process conserved from bacteria to humans. In bacteria, sigma factors are employed to mediate gene-specific expression in response to a vari...
作者:... Ioly Kotta-Loizou , Martin Buck , Xiaodong Zhang
来源:[J].Molecular Cell(IF 15.28), 2018, Vol.70 (6), pp.1111-1120.e3
摘要:Summary(#br)Gene transcription is carried out by multi-subunit RNA polymerases (RNAPs). Transcription initiation is a dynamic multi-step process that involves the opening of the double-stranded DNA to form a transcription bubble and delivery of the template strand deep into ...
作者:Robert W. Bradley , Martin Buck , Baojun Wang
来源:[J].Journal of Molecular Biology(IF 3.905), 2016, Vol.428 (5), pp.862-888
摘要:Abstract(#br)Synthetic biologists aim to construct novel genetic circuits with useful applications through rational design and forward engineering. Given the complexity of signal processing that occurs in natural biological systems, engineered microbes have the potential to perfo...
作者:... Roman Tuma , Peter Stockley , Martin Buck
来源:[J].Journal of Molecular Biology(IF 3.905), 2015, Vol.427 (22), pp.3516-3526
摘要:Abstract(#br)In bacterial RNA polymerase (RNAP), the bridge helix and switch regions form an intricate network with the catalytic active centre and the main channel. These interactions are important for catalysis, hydrolysis and clamp domain movement. By targeting conserved ...
作者:... Goran Jovanovic , Ioly Kotta-Loizou , Martin Buck
来源:[J].Analytical Biochemistry(IF 2.582), 2016, Vol.503, pp.56-57
摘要:Abstract(#br)Historically, the lacZ gene is one of the most universally used reporters of gene expression in molecular biology. Its activity can be quantified using an artificial substrate, o -nitrophenyl-ß- d -galactopyranoside (ONPG). However, the traditional method for me...
作者:Robert W Bradley , Martin Buck , Baojun Wang
来源:[J].Current Opinion in Microbiology(IF 8.23), 2016, Vol.33, pp.74-82
摘要:A central aim of synthetic biology is to build organisms that can perform useful activities in response to specified conditions. The digital computing paradigm which has proved so successful in electrical engineering is being mapped to synthetic biological systems to allow them t...

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