全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Marta Struga , Izabela Dybala ...
来源:[J].Molecules(IF 2.428), 2009, Vol.14 (12), pp.5189DOAJ
摘要:A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent hu...
作者:Magdalena Mielczarek-Puta , Marta Struga , Piotr Roszkowski
来源:[J].Medicinal Chemistry Research(IF 1.612), 2019, Vol.28 (12), pp.2153-2164Springer
摘要:Abstract(#br)Doxorubicin (DOX) is a leading cytostatic drug with many adverse effects in use. We are still looking for methods that will allow us to preserve the therapeutic effect against the tumor cells and reduce the toxicity to the normal cells. In our work, we obtained ...
作者:... Anna E. Kozioł , Izabela Dybała , Marta Struga
来源:[J].Molecules(IF 2.428), 2008, Vol.13 (8), pp.1570DOAJ
摘要:A series of twenty six arylpiperazine and aminoalkanol derivatives of 4-azatricyclo[ 5.2.2.02,6]undecane-3,5,8-trione have been prepared. The synthesized compounds were evaluated for their cytotoxicity and anti-HIV-1 activity in MT-4 cells.
作者:Michał A. Dobrowolski , Marta Struga , Daniel Szulczyk
来源:[J].Acta Crystallographica Section E(IF 0.347), 2011, Vol.67 (12), pp.o3446-o3447DOAJ
摘要:The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS) for the two cyclic fragments of the ...
作者:Marta Struga , Jerzy Kossakowski
来源:[J].Molecules(IF 2.428), 2009, Vol.14 (12), pp.5189-5202DOAJ
摘要:A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent hu...
作者:... Daniel Szulczyk , Anna E. Koziol , Marta Struga
来源:[J].Acta Crystallographica Section E(IF 0.347), 2011, Vol.67 (11), pp.o3010-o3010DOAJ
摘要:The title compound, C10H12FN3S, crystallizes in the same space group (P21/c) as two polymorphic forms of 4-phenyl-1-(propan-2-ylidene)thiosemicarbazone [Jian et al. (2005). Acta Cryst. E61, o653–o654; Venkatraman et al. (2005). Acta Cryst. E61, o3914–o3916]. The arran...
作者:... Anna E. Koziol , Magdalena Pakosinska-Parys , Marta Struga
来源:[J].Acta Crystallographica Section E(IF 0.347), 2012, Vol.68 (12), pp.o3293-o3294DOAJ
摘要:In the title compound, C20H17NO3 (alternative name: N-hydroxy-9,10-dimethyl-9,10-ethanoanthracene-11,12-dicarboximide), the rigid ethanoanthracene-dicarboximide moiety has a roof-shaped geometry, the interplanar angle between the two terminal phenyl rings being 124.9 (6)...
作者:... Mariola Krawiecka , Bożena Kuran , Marta Struga
来源:[J].Medicinal Chemistry Research(IF 1.612), 2014, Vol.23 (3), pp.1519-1536Springer
摘要:Abstract(#br)A series of arylpiperazine derivatives of 1,16-diphenyl-19-azahexacyclo-[14.5.1.0 2,15 .0 3,8 .0 9,14 .0 17,21 ]docosa-2,3,5,7,8,9,11,13,14-nonaene-18,20,22-trione and 4,10-diphenyl-1 H ,2 H ,3 H ,5 H -indeno[1,2- f ]isoindole-1,3,5-trione was synthesized. The pharma...
作者:Marta Struga , Anna Partyka
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2019, Vol.27 (18), pp.4163-4173Elsevier
摘要:Abstract(#br)On the basis of the structures of serotonin modulators or drugs (NAN-190, buspirone, aripiprazole) and phosphodiesterase 4 (PDE4) inhibitors (rolipram, RO-20-1724), a series of novel multitarget 5-arylidenehydantoin derivatives with arylpiperazine fragment was s...

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