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作者:... Timothy J. Kidd , Scott A. Beatson , Mark A. Schembri
来源:[J].Trends in Microbiology(IF 8.434), 2017, Vol.25 (9), pp.729-740
摘要:Uropathogenic Escherichia coli (UPEC) is a pathogen of major significance to global human health and is strongly associated with rapidly increasing antibiotic resistance. UPEC is the primary cause of urinary tract infection (UTI), a disease that involves a complicated pathog...
作者:Mark A. Schembri , Rowland N. Cobbold ...
来源:[J].Journal of Controlled Release(IF 7.633), 2018
摘要:Abstract(#br)Currently, there are few strategies for controlling pathogenic bacteria, especially the pathotypes of Escherichia coli which are an emerging threat to public health worldwide. Here, multivalent vaccine formulations are reported for control of pathogenic E. coli ...
作者:... Richard I. Webb , Danilo G. Moriel , Mark A. Schembri
来源:[J].Journal of Proteomics(IF 4.088), 2016, Vol.131, pp.177-189
摘要:Abstract(#br)Uropathogenic Escherichia coli (UPEC) are the primary cause of urinary tract infection (UTI) in humans. For the successful colonisation of the human urinary tract, UPEC employ a diverse collection of secreted or surface-exposed virulence factors including toxins, iro...
作者:... Makrina Totsika , Donna M. Easton , Mark A. Schembri
来源:[J].Journal of Proteomics(IF 4.088), 2015, Vol.115, pp.93-106
摘要:Abstract(#br)Uropathogenic Escherichia coli (UPEC) are the major cause of urinary tract infections. For successful colonisation of the urinary tract, UPEC employ multiple surface-exposed or secreted virulence factors, including adhesins and iron uptake systems. Whilst individual ...
作者:Mark A. Schembri , Paul C. Mills ...
来源:[J].Veterinary Microbiology(IF 3.127), 2011, Vol.147 (1-2), pp.205-208
摘要:Abstract(#br)Establishment of asymptomatic bacteriuria (ABU) with Escherichia coli 83972 is a viable prophylactic alternative to antibiotic therapy for the prevention of recurrent bacterial urinary tract infection in humans. Approximately 2 × 10 8 viable E. coli 83972 cells ...
作者:Mark A. Schembri , Paul C. Mills
来源:[J].Veterinary Microbiology(IF 3.127), 2012, Vol.158 (3-4), pp.446-450
摘要:Abstract(#br)Establishment of asymptomatic bacteriuria is a novel alternative to antimicrobial therapy for management of recurrent bacterial urinary tract infection in humans and may also be useful for dogs if it can be shown that colonization of the canine bladder can be achieve...
作者:Per Klemm , Mark A. Schembri
来源:[J].International Journal of Medical Microbiology(IF 4.537), 2000, Vol.290 (3), pp.215-221
摘要:Abstract(#br)The display of peptide segments on the surface of bacteria offers many new and exciting applications in biotechnology and medical research. Fimbria-assisted display of heterologous sequences is a paradigm for chimeric organelle display on bacteria. Fimbriae are parti...
作者:Per Klemm , Mark A. Schembri
来源:[J].International Journal of Medical Microbiology(IF 4.537), 2000, Vol.290 (1), pp.27-35
摘要:Abstract(#br)Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine bacterial attachment to host tissue surfaces are mediated by microbial adhesins. Host specificity and tissue tropism are char...
作者:... Glen C. Ulett , Mark A. Schembri , Matthew J. Sweet
来源:[J].Immunobiology(IF 2.814), 2011, Vol.216 (11), pp.1164-1171
摘要:Abstract(#br)Uropathogenic E. coli (UPEC) are the primary cause of urinary tract infections. Recent studies have demonstrated that UPEC can invade and replicate within epithelial cells, suggesting that this bacterial pathogen may occupy an intracellular niche within the host. Giv...
作者:... Graeme R. Nimmo , Catharina Svanborg , Mark A. Schembri
来源:[J].International Journal of Medical Microbiology(IF 4.537), 2008, Vol.299 (1), pp.53-63
摘要:Abstract(#br)In asymptomatic bacteriuria (ABU), bacteria colonize the urinary tract without provoking symptoms. Here, we compared the virulence properties of a collection of ABU Escherichia coli strains to cystitis and pyelonephritis strains. Specific urinary tract infection (UTI...

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