全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Maria Cristina De Rosa , Davide Pirolli ...
来源:[J].BMC Genetics(IF 2.808), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)The two homologous iron-binding lobes of transferrins are thought to have evolved by gene duplication of an ancestral monolobal form, but any conserved synteny between bilobal and monolobal transferrin loci remains unexplored. The important role playe...
作者:... Paola Concolino , Bruno Giardina , Maria Cristina De Rosa
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2010, Vol.12 (1), pp.128DOAJ
摘要:The majority of inactivating mutations of p53 reside in the central core DNA binding domain of the protein. In this computational study, we investigated the structural effects of a novel p53 mutation (G389E), identified in a patient with congenital adrenal hyperplasia, which...
作者:Maria Cristina De Rosa , Bruno Giardina ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2010, Vol.12 (1), pp.128-140DOAJ
摘要:The majority of inactivating mutations of p53 reside in the central core DNA binding domain of the protein. In this computational study, we investigated the structural effects of a novel p53 mutation (G389E), identified in a patient with congenital adrenal hyperplasia, which...
作者:... Giorgio Conti , Daniele De Luca , Maria Cristina De Rosa
来源:[J].Journal of Molecular Graphics and Modelling(IF 2.325), 2018, Vol.81, pp.68-76Elsevier
摘要:Abstract(#br)Phospholipase A2-IIA catalyzes the hydrolysis of the sn-2 ester of glycerophospholipids. A rare c.428G > A (p.Arg143His) variant in PLA2G2A gene was found in two infants affected by acute respiratory distress syndrome (ARDS) by whole coding region and exon/intron bou...
作者:Maria Cristina De Rosa , Kim Præbel ...
来源:[J].Marine Genomics(IF 1.339), 2015, Vol.22, pp.45-54Elsevier
摘要:Abstract(#br)The synaptophysin (SYP) family comprises integral membrane proteins involved in vesicle-trafficking events, but the physiological function of several members has been enigmatic for decades. The presynaptic SYP protein controls neurotransmitter release, while SYP...
作者:Maria Cristina De Rosa , Bruno Giardina
来源:[J].Biochimie(IF 3.142), 2012, Vol.94 (2), pp.393-402Elsevier
摘要:Abstract(#br)The aim of this research was to investigate the effect of caffeine on band 3 (the anion exchanger protein), haemoglobin function, caspase 3 activation and glucose-6-phosphate metabolism during the oxygenation–deoxygenation cycle in human red blood cells. A parti...
作者:... Alvaro Mordente , Silvana Ficarra , Maria Cristina De Rosa
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2012, Vol.56, pp.145-154Elsevier
摘要:Abstract(#br)The anthracycline anticancer agents daunorubicin (DAUN) and doxorubicin (DOX) are reduced by different NADPH-dependent cytosolic reductases into their corresponding alcohol metabolites daunorubicinol (DAUNol) and doxorubicinol (DOXol), which have been implicated in t...

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