全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Mari Kyllesø Halle , Helga B. Salvesen ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact ...
作者:Mari Kyllesø Halle , Anne M Øyan ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (12)DOAJ
摘要:BACKGROUND: Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, underlying molecular characteristics of primary and metastat...
作者:Mari Kyllesø Halle , Akinyemi I. Ojesina ...
来源:[J].American Journal of Obstetrics and Gynecology(IF 3.877), 2017Elsevier
摘要:Background(#br)Cervical cancer is a major health problem worldwide. Identification of effective clinicopathologic and molecular markers is vital to improve treatment stratification.(#br)Objectives(#br)The purpose of this study was to validate a set of well-defined clinicopat...
作者:Mari Kyllesø Halle , Camilla Krakstad ...
来源:[J].Pathology - Research and Practice(IF 1.213), 2014, Vol.210 (11), pp.774-778Elsevier
摘要:Abstract(#br)Many emerging tools for comprehensive molecular profiling of malignant lesions demand fresh frozen tissue with a high tumor purity. Often, a tumor epithelial content of at least 80% is recommended. This approach may lead to a systematic bias, and therefore we explore...
作者:Mari Kyllesø Halle , Hilde Sundvold ...
来源:[J].Gene(IF 2.196), 2014, Vol.543 (2), pp.268-274Elsevier
摘要:Abstract(#br)In mammals, two carotenoid cleaving oxygenases are known; beta-carotene 15,15′-monooxygenase (BCMO1) and beta-carotene 9′,10′-oxygenase (BCO2). BCMO1 is a key enzyme in vitamin A synthesis by symmetrically cleaving beta-carotene into 2 molecules of all- tra...
作者:Mari Kyllesø Halle , Helga B. Salvesen ...
来源:[J].Tumor Biology(IF 2.518), 2016, Vol.37 (8), pp.10697-10702Springer
摘要:Abstract(#br)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in several cancer forms. Recently, a single...
作者:Mari Kyllesø Halle , Anne M. Øyan ...
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (12)PLOS
摘要:Despite being the most common pelvic gynecologic malignancy in industrialized countries, no targeted therapies are available for patients with metastatic endometrial carcinoma. In order to improve treatment, underlying molecular characteristics of primary and metastatic disease m...

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