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作者:... Anna Szarpak-Jankowska , Rachel Auzély-Velty , Marcos Luciano Bruschi
来源:[J].Journal of Molecular Liquids(IF 1.684), 2020, Vol.303
摘要:Abstract(#br)Microsponges (MS) have shown great potential for the incorporation of relatively higher amounts of drugs. This is due to the presence of both surface pores and interconnected channels that provide a greater contact area for the absorption of active agents. Howev...
作者:Marcos Luciano Bruschi , Elza Kimura ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.142
摘要:Abstract(#br)Bromopride is a prokinetic and antiemetic drug used to treat nausea and vomiting. Although its prescription is common in Brazil, there is a lack of studies about bromopride pharmacokinetics. Therefore, the aims of this study were to investigate the population ph...
作者:... Fernanda Belincanta Borghi-Pangoni , Raquel Guttierres Gomes , Marcos Luciano Bruschi
来源:[J].Journal of the Mechanical Behavior of Biomedical Materials(IF 2.368), 2017, Vol.74, pp.142-153
摘要:Abstract(#br)Pluronic F127 ® was associated with a carbomer homopolymer type B, as a model polymer blend to evidence the information provided by rheological and mechanical analyses on the development of bioadhesive thermoresponsive systems. The mechanical analysis enabled to...
作者:... Giuseppe Valacchi , Rita Cortesi , Marcos Luciano Bruschi
来源:[J].Colloids and Surfaces B: Biointerfaces(IF 3.554), 2017, Vol.158, pp.441-452
摘要:Abstract(#br)Propolis, a natural compound that can accelerate the wound healing process, is mainly used as ethanolic extract. The extractive solution may also be obtained from the propolis by-product (BP), transforming this waste material into a pharmaceutical active ingredient. ...
作者:... Fernanda Belincanta Borghi-Pangoni , Mariana Volpato Junqueira , Marcos Luciano Bruschi
来源:[J].Journal of the Mechanical Behavior of Biomedical Materials(IF 2.368), 2017, Vol.68, pp.265-275
摘要:Abstract(#br)Polycarbophil is widely used in a variety of pharmaceutical formulations, mainly for their strong ability to adhere to the epithelial and mucous barriers (bio/mucoadhesion). On the other hand, its association with the thermoresponsive polymer (poloxamer 407) has been...
作者:... Rafaela Said dos Santos , Sabrina Barbosa de Souza Ferreira , Marcos Luciano Bruschi
来源:[J].Journal of Molecular Liquids(IF 1.684), 2019, Vol.289
摘要:Abstract(#br)The present work at hands deals with physicochemical properties of an organogel composed of non-ionic triblock copolymer poloxamer 188 and passion fruit oil. To provide the characterization it was investigated the rheological (continuous shear and oscillatory) proper...
作者:... Andréa Diniz , Wilker Caetano , Marcos Luciano Bruschi
来源:[J].Photodiagnosis and Photodynamic Therapy(IF 2.243), 2017, Vol.19, pp.284-297
摘要:Abstract(#br)Hypericin (Hyp) is a natural photoactive pigment utilized in the treatment of different types of cancer and antimicrobial inactivation using photodynamic therapy (PDT). Hyp is poorly soluble in water leading to problems of administration, getting close contact with t...
作者:... Sabrina Barbosa de Souza Ferreira , Marcos Luciano Bruschi , Graciette Matioli
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (2)
摘要:Curdlan is a linear polysaccharide considered a dietary fiber and with gelation properties. This study evaluated the structure, morphology and the physicochemical and technological properties of curdlan produced by Agrobacterium sp. IFO 13140 recovered by pre-gelation and pr...
作者:... Adriano Valim Reis , Michael Thomas Cook , Marcos Luciano Bruschi
来源:[J].Polymers(IF 1.687), 2018, Vol.10 (3)
摘要:The process of mucoadhesion has been widely studied using a wide variety of methods, which are influenced by instrumental variables and experiment design, making the comparison between the results of different studies difficult. The aim of this work was to standardize the co...
作者:... Michael J. Parnham , Marcos Luciano Bruschi , Matthias G. Wacker
来源:[J].International Journal of Pharmaceutics(IF 3.458), 2015, Vol.491 (1-2), pp.250-260
摘要:Abstract(#br)The development and manufacture of novel nanocarriers for drug delivery has proved challenging with regards to scale-up and pharmaceutical quality. Polymeric nanocarriers composed of poly(lactic- co -glycolic acid)- b -poly(ethylene glycol) (PLGA–PEG) were prepa...

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