全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Ayesha A. Shafi , Manjula Nakka , Nancy L. Weigel
来源:[J].International Journal of Biochemistry and Cell Biology(IF 4.152), 2014, Vol.54, pp.49-59Elsevier
摘要:Abstract(#br)Prostate cancer (PCa) is an androgen-dependent disease, and tumors that are resistant to androgen ablation therapy often remain androgen receptor (AR) dependent. Among the contributors to castration-resistant PCa are AR splice variants that lack the ligand-binding do...
作者:Manjula Nakka , Irina U. Agoulnik , Nancy L. Weigel
来源:[J].International Journal of Biochemistry and Cell Biology(IF 4.152), 2013, Vol.45 (4), pp.763-772Elsevier
摘要:Abstract(#br)The evidence that androgen blockade-resistant prostate cancer, termed castration resistant, remains androgen receptor (AR) dependent is compelling. AR is re-activated through multiple mechanisms including expression of constitutively active splice variants that lack ...
作者:Manjula Nakka , Ramesh B. Iyer , Leonidas G. Bachas
来源:[J].The Protein Journal(IF 1.126), 2006, Vol.25 (1), pp.17-21Springer
摘要:Proteins from thermophilic microorganisms are stabilized by various mechanisms to preserve their native folded states at higher temperatures. A thermostable glucose-6-phosphate dehydrogenase (tG6PDH) from the hyperthermophilic bacterium Aquifex aeolicus was expressed as a re...
作者:Manjula Nakka , Xiang Chen ...
来源:[J].Advances in Modern Oncology Research, 2017, Vol.3 (4)PiscoMed Publishing
摘要:In the age of big data, genomics and clinical research have reached a crossroads. A wealth of data is being generated, but it is becoming increasingly complicated to analyze these data to extract meaningful results. The ability to understand biological systems holistically h...

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