全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Mamoru Takeda , Yoshiyuki Tsuboi ...
来源:[J].Molecular Pain(IF 3.774), 2011, Vol.7 (1)Springer
摘要:Abstract(#br)Previous studies in several different trigeminal nerve injury/inflammation models indicated that the hyperexcitability of primary afferent neurons contributes to the pain pathway underlying mechanical allodynia. Although multiple types of voltage-gated ion channels a...
作者:Mamoru Takeda , Masamichi Shinoda ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2016, Vol.66 (5), pp.381-386Springer
摘要:Abstract(#br)Peripheral tissue inflammation can alter the properties of somatic sensory pathways, causing behavioral hypersensitivity and resulting in increased responses to pain caused by noxious stimulation (hyperalgesia) and normally innocuous stimulation (allodynia). The...
作者:Mamoru Takeda , Masanori Nasu ...
来源:[J].Neuroscience Research(IF 2.204), 2018, Vol.128, pp.25-32Elsevier
摘要:Abstract(#br)This study investigated the functional significance of hyperalgesia in the CCL2/CCR2 signaling system in trigeminal ganglion (TG) neurons following inflammation. Inflammation was induced by injection of complete Freund’s adjuvant (CFA) into the whisker pad of ra...
作者:Mamoru Takeda , Masayuki Takahashi ...
来源:[J].Brain Behavior and Immunity(IF 5.612), 2013, Vol.28, pp.100-107Elsevier
摘要:Abstract(#br)Previous our report indicated that acute application of glial cell line-derived neurotrophic factor (GDNF) enhances the neuronal excitability of adult rat small-diameter trigeminal ganglion (TRG) neurons, which innervate the facial skin in the absence of neuropa...
作者:... Katsuo Oshima , Yoshihito Shimazu , Mamoru Takeda
来源:[J].Neuroscience Research(IF 2.204), 2017, Vol.119, pp.1-6Elsevier
摘要:Abstract(#br)The aim of the present study was to investigate whether, under in vivo conditions, systemic administration of resveratrol could attenuate the rat nociceptive jaw-opening reflex (JOR) via the endogenous opioid system. The JOR evoked by electrical stimulation of t...
作者:... Kei Yui , Yoshihito Shimazu , Mamoru Takeda
来源:[J].Brain Research Bulletin(IF 2.935), 2017, Vol.131, pp.70-77Elsevier
摘要:Abstract(#br)Theanine is a non-dietary amino acid linked to the modulation of synaptic transmission in the central nervous system, although the acute effects of theanine in vivo, particularly on nociceptive transmission in the trigeminal system, remain to be determined. The ...
作者:... Katsuo Oshima , Yoshihito Shimazu , Mamoru Takeda
来源:[J].Neuroscience Research(IF 2.204), 2018Elsevier
摘要:Abstract(#br)Although docosahexaenoic acid (DHA) administration suppresses sodium channels in primary afferent sensory neurons, the acute local effect of DHA on the trigeminal nociceptive reflex remains to be elucidated, in vivo. Therefore, the aim of the present study was t...
作者:Mamoru Takeda , Masayuki Takahashi , Shigeji Matsumoto
来源:[J].Brain Behavior and Immunity(IF 5.612), 2008, Vol.22 (7), pp.1016-1023Elsevier
摘要:Abstract(#br)The present study investigated whether under in vivo conditions, inflammation alters the excitability of nociceptive Aδ-trigeminal ganglion (TRG) neurons innervating the facial skin via a cytokine paracrine mechanism. We used extracellular electrophysiological r...

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