全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Nathir M. Obeidat , Tareq M. Mahafza , Malek A. Zihlif
来源:[J].BMC Medical Genetics(IF 2.536), 2017, Vol.18 (1)Springer
摘要:Asthma and allergic rhinitis are respiratory diseases with a significant global burden. Forkhead box O3 ( FOXO3 ) is a gene involved in the etiology of a number of respiratory diseases. The objective of this study is to assess the association of rs13217795, an intronic FOXO3 sing...
作者:Malek A. Zihlif , Randa G. Naffa
来源:[J].Molecules(IF 2.428), 2011, Vol.16 (5), pp.4305DOAJ
摘要:A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines. The chemical structures of the newly prepared compoun...
作者:Malek A. Zihlif , Eman D. Awad ...
来源:[J].Molecules(IF 2.428), 2011, Vol.17 (1), pp.227-239DOAJ
摘要:A new series of 6-substituted-4-methyl-3-(4-arylpiperazin-1-yl)cinnolines 8–10 were synthesized as potential antifungal agents via intramolecular cyclization of the respective 1-(2-arylhydrazono)-1-(4-arylpiperazin-1-yl)propan-2-ones 5–7, mediated by polyphosphoric acid (PPA...
作者:Malek A. Zihlif , Randa G. Naffa
来源:[J].Molecules(IF 2.428), 2011, Vol.16 (5), pp.4305-4317DOAJ
摘要:A series of new N1-(coumarin-7-yl)amidrazones incorporating N-piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-amino-4-methylcoumarin with the appropriate piperazines. The chemical structures of the newly prepared compoun...
作者:Feda' H. Hamdan , Malek A. Zihlif
来源:[J].Genomics(IF 3.01), 2014, Vol.104 (6), pp.477-481Elsevier
摘要:Abstract(#br)Hypoxia plays a significant role in tumor progression and aggressiveness and implicated in resistance to radiotherapy and chemotherapy. This study aims to characterize the changes in gene expression associated with chronic hypoxia in MCF7 breast cancer cell line and ...
作者:... Abdulla S. Awidi , Mamoun Ahram , Malek A. Zihlif
来源:[J].Gene(IF 2.196), 2016, Vol.575 (2), pp.415-420Elsevier
摘要:Abstract(#br)Development of resistance against cancer therapeutic agents is a common problem in cancer management. Trastuzumab resistance is one of the challenges in management of HER-2-positive breast cancer patients resulting in breast cancer progression, metastasis, and p...
作者:Malek A. Zihlif , Mutasem O. Taha
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2012, Vol.54, pp.65-74Elsevier
摘要:Abstract(#br)A series of new N 1-(flavon-7-yl)amidrazones incorporating N -piperazines and related congeners were synthesized by reacting the hydrazonoyl chloride derived from 7-aminoflavone and 7-amino-2-methylchromen-4-one with the appropriate piperazine. The chemical stru...

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