全部文献期刊会议图书|学者科研项目
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作者:Maldonado Emanuel , Li Cai ...
来源:[J].Molecular Biology and Evolution(IF 10.353), 2015, Vol.32 (11), pp.2832-2843
摘要:Olfactory receptors (ORs) govern a prime sensory function. Extant birds have distinct olfactory abilities, but the molecular mechanisms underlining diversification and specialization remain mostly unknown. We explored OR diversity in 48 phylogenetic and ecologically diverse ...
作者:Maldonado Emanuel , Antunes Agostinho
来源:[J].BMC bioinformatics(IF 3.024), 2019, Vol.20 (1), pp.739
摘要:BACKGROUND(#br)Recent advances in genome sequencing technologies and the cost drop in high-throughput sequencing continue to give rise to a deluge of data available for downstream analyses. Among others, evolutionary biologists often make use of genomic data to uncover phenotypic...
作者:Maldonado Emanuel , Almeida Daniela ...
来源:[J].BMC bioinformatics(IF 3.024), 2016, Vol.17 (1), pp.354
摘要:BACKGROUND(#br)Uncovering how phenotypic diversity arises and is maintained in nature has long been a major interest of evolutionary biologists. Recent advances in genome sequencing technologies have remarkably increased the efficiency to pinpoint genes involved in the adaptive e...
作者:Maldonado Emanuel , O'Brien Stephen J ...
来源:[J].Genome biology and evolution(IF 4.759), 2016, Vol.8 (9), pp.2748-59
摘要:A diverse group of genes are involved in the tooth development of mammals. Several studies, focused mainly on mice and rats, have provided a detailed depiction of the processes coordinating tooth formation and shape. Here we surveyed 236 tooth-associated genes in 39 mammalia...
作者:Maldonado Emanuel , Vasconcelos Vitor
来源:[J].PloS one(IF 3.73), 2015, Vol.10 (8), pp.e0135405
摘要:Mitochondrial protein-coding genes (mt genes) encode subunits forming complexes of crucial cellular pathways, including those involved in the vital process of oxidative phosphorylation (OXPHOS). Despite the vital role of the mitochondrial genome (mt genome) in the survival of org...
作者:Maldonado Emanuel , Khan Imran ...
来源:[J].Genome biology and evolution(IF 4.759), 2016, Vol.8 (4), pp.1115-31
摘要:The cytochrome P450 (CYP) superfamily defends organisms from endogenous and noxious environmental compounds, and thus is crucial for survival. However, beyond mammals the molecular evolution of CYP2 subfamilies is poorly understood. Here, we characterized the CYP2 family across 4...
作者:Maldonado Emanuel , Khan Imran ...
来源:[J].Evolutionary bioinformatics online(IF 1.326), 2013, Vol.9, pp.487-90
摘要:The rapid advances in genome sequencing technologies have increased the pace at which biological sequence databases are becoming available to the broad scientific community. Thus, obtaining and preparing an appropriate sequence dataset is a crucial first step for all types of gen...
作者:Maldonado Emanuel , Sunagar Kartik ...
来源:[J].PloS one(IF 3.73), 2014, Vol.9 (10), pp.e96243
摘要:Among the major goals of research in evolutionary biology are the identification of genes targeted by natural selection and understanding how various regimes of evolution affect the fitness of an organism. In particular, adaptive evolution enables organisms to adapt to changing e...
作者:Maldonado Emanuel , de la Riva Gustavo ...
来源:[J].PloS one(IF 3.73), 2013, Vol.8 (7), pp.e65926
摘要:The introduction of two-dimension (2D) graphs and their numerical characterization for comparative analyses of DNA/RNA and protein sequences without the need of sequence alignments is an active yet recent research topic in bioinformatics. Here, we used a 2D artificial representat...

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