全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Makoto Bonkobara , Masaki Michishita ...
来源:[J].BMC Veterinary Research(IF 1.861), 2017, Vol.13 (1)Springer
摘要:The pathological condition of canine prostate cancer resembles that of human androgen-independent prostate cancer. Both canine and human androgen receptor (AR) signalling are inhibited by overexpression of the dimerized co-chaperone small glutamine-rich tetratricopeptide rep...
作者:... Masato Kobayashi , Makoto Bonkobara , Masamine Takanosu
来源:[J].Veterinary Immunology and Immunopathology(IF 1.877), 2017, Vol.188, pp.84-88Elsevier
摘要:Abstract(#br)Imatinib-resistance is a major therapeutic problem in human chronic myeloid leukemia, human gastrointestinal stromal tumors, and canine mast cell tumors. In the present study, we identified the secondary mutation c.2006C > T in c-KIT exon 14 in a mast cell tumor obta...
作者:... Yoshikazu Tanaka , Kyoichi Tamura , Makoto Bonkobara
来源:[J].Veterinary Immunology and Immunopathology(IF 1.877), 2018, Vol.201, pp.72-76Elsevier
摘要:Abstract(#br)Feline histiocytic sarcoma (HS) is an aggressive and uncommon tumor originating from dendritic cells/macrophages. Here, a feline HS cell line, FHS-1, was established from a case of feline HS and characterized. Immunohistochemically, FHS-1 cells were positive for...
作者:... Masato Kobayashi , Kyoichi Tamura , Makoto Bonkobara
来源:[J].The Veterinary Journal(IF 2.424), 2018Elsevier
摘要:Abstract(#br)Treatment of unresectable canine squamous cell carcinoma (SCC) remains challenging and new therapeutic strategies are needed. Survivin is a member of the inhibitor of apoptosis protein family and its inhibitor, YM155, is a potential anti-tumour agent. In the present ...
作者:Makoto Bonkobara
来源:[J].The Veterinary Journal(IF 2.424), 2015, Vol.205 (2), pp.180-188Elsevier
摘要:Abstract(#br)Imatinib inhibits the activity of several tyrosine kinases, including BCR-ABL, KIT and platelet-derived growth factor receptor (PDGFR). Dysregulation of KIT is found in mast cell tumours (MCTs) and KIT is mutated in approximately 30% and 70% of canine and feline MCTs...
作者:Makoto Bonkobara , Masanori Kobayashi ...
来源:[J].The Veterinary Journal(IF 2.424), 2015, Vol.206 (2), pp.143-148Elsevier
摘要:Abstract(#br)Although the morbidity of canine prostate cancer is low, the majority of cases present with resistance to androgen therapy and poor clinical outcomes. These pathological conditions are similar to the signs of the terminal stage of human androgen-independent pros...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×