全部文献期刊会议图书|学者科研项目
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作者:Mário Sérgio Mantovani , Andreas Lazaros Chryssafidis ...
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-9DOAJ
摘要:Abstract The present study tested the effects of a newly identified indolin-3-one compound (compound 1, produced by Pseudomonas aeruginosa, on HepG2 cells. The MTT assays demonstrated decreased metabolic activities in HepG2 cells treated with compound 1, with dose- and time-...
作者:... Chris T. Evelo , Mário Sérgio Mantovani , Lúcia Regina Ribeiro
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.48 (1), pp.397-408DOAJ
摘要:Background/Aims: Compared with non-obese individuals, obese individuals commonly store more vitamin D in adipose tissue. VDR expression in adipose tissue can influence adipogenesis and is therefore a target pathway deserving further study. This study aims to assess the role of 1,...
作者:Mário Sérgio Mantovani , Augusto Ferreira da Eira ...
来源:[J].Genetics and Molecular Biology(IF 0.744), 2005, Vol.28 (3), pp.458-463DOAJ
摘要:Agaricus blazei Murrill, popularly known as the sun mushroom, is a native mushroom in SP, Brazil, that has been widely used in the treatment of cancer and many other pathologies in different parts of the world. A water-soluble protein-polysaccharide complex (1 -> 6)beta-D-glucan ...
作者:... Berenice Quinzani Jordão , Lúcia Regina Ribeiro , Mário Sérgio Mantovani
来源:[J].Genetics and Molecular Biology(IF 0.744), 2008, Vol.31 (1), pp.122-127DOAJ
摘要:Functional food investigations have demonstrated the presence of substances that could be beneficial to human health when consumed. However, the toxic effects of some substances contained in foods have been determined. Reported medicinal and nutritive properties have led to the e...
作者:Janaina Rigonato , Mário Sérgio Mantovani , Berenice Quinzani Jordão
来源:[J].Genetics and Molecular Biology(IF 0.744), 2005, Vol.28 (3), pp.464-468DOAJ
摘要:The comet assay was used to study the sensitivity of the widely distributed freshwater bivalve mollusk Corbicula fluminea to the DNA-damaging alkylating-agent methylmethane sulfonate (MMS). This study was undertaken to ascertain if C. fluminea is a good bioindicator of pollutants...
作者:Mário Sérgio Mantovani , Claudia Masrouah Jamal ...
来源:[J].Genetics and Molecular Biology(IF 0.744), 2010, Vol.33 (1), pp.176-181DOAJ
摘要:An aqueous extract of Rhizophora mangle L. bark is used as raw material in pottery making in the State of Espirito Santo, Brazil. This extract presents large quantities of tannins, compounds possessing antioxidant properties. Tannin antioxidant activity, as a plant chemical defen...
作者:... Rosangela de Oliveira Teixeira , Mário Sérgio Mantovani , Veronica Elisa Pimenta Vicentini
来源:[J].Genetics and Molecular Biology(IF 0.744), 2002, Vol.25 (1), pp.85-89DOAJ
摘要:Medicinal plants are widely used to treat various diseases, and in Brazil the plants Maytenus ilicifolia Mart. and Bauhinia candicans Benth are commonly used in popular medicine. However, there are a large number of compounds in plants which can produce alterations in genetic mat...
作者:Mário Sérgio Mantovani , Mirtis Irene Ariza Malaguttii ...
来源:[J].Genetics and Molecular Biology(IF 0.744), 2006, Vol.29 (1), pp.148-158DOAJ
摘要:Cytotoxicity of metals is important because some metals are potential mutagens able to induce tumors in humans and experimental animals. Chromium can damage DNA in several ways, including DNA double strand breaks (DSBs) which generate chromosomal aberrations, micronucleus fo...
作者:Mário Sérgio Mantovani , Carmen Luisa Barbosa Guedes
来源:[J].Genetics and Molecular Biology(IF 0.744), 2010, Vol.33 (1), pp.169-175DOAJ
摘要:Polycyclic aromatic hydrocarbons (PAHs) are genotoxic chemicals commonly found in effluents from oil refineries. Bioassays using plants and cells cultures can be employed for assessing environmental safety and potential genotoxicity. In this study, the genotoxic potential of an o...

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