全部文献期刊会议图书|学者科研项目
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作者:Lutgarde Thijs , Erika Salvi ...
来源:[J].BMC Medical Genetics(IF 2.536), 2017, Vol.18 (1)Springer
摘要:Platelet Endothelial Aggregation Receptor 1 (PEAR1), a membrane protein highly expressed in platelets and endothelial cells, plays a role in platelet contact-induced activation, sustained platelet aggregation and endothelial function. Previous reports implicate PEAR1 rs12041331 a...
作者:Lutgarde Thijs , Zhen-Yu Zhang ...
来源:[J].BMC Genetics(IF 2.808), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)In mice MEOX2/TCF15 heterodimers are highly expressed in heart endothelial cells and are involved in the transcriptional regulation of lipid transport. In a general population, we investigated whether genetic variation in these genes predicted co...
作者:Lutgarde Thijs , Katarzyna Stolarz-Skrzypek ...
来源:[J].Trials(IF 2.206), 2011, Vol.12 (1)Springer
摘要:Background(#br)The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K<...
作者:Lutgarde Thijs , Kei Asayama ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (8)DOAJ
摘要:In the Systolic Hypertension in Europe trial (NCT02088450), we investigated whether systolic blood pressure variability determines prognosis over and beyond level.Using a computerised random function and a double-blind design, we randomly allocated 4695 patients (≥60 years) ...
作者:Lutgarde Thijs , Jan A Staessen
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (10)DOAJ
摘要:Detecting left ventricular (LV) dysfunction at an early stage is key in addressing the heart failure epidemic. In proteome profiling experiments in mice subjected either to aortic banding or sham, the circulating CXCR3 ligands monokine induced by interferon-γ (MIG) and inter...
作者:Lutgarde Thijs , Yu Jin ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (5)DOAJ
摘要:BACKGROUND: Indoxyl sulfate and p-cresyl sulfate are unique microbial co-metabolites. Both co-metabolites have been involved in the pathogenesis of accelerated cardiovascular disease and renal disease progression. Available evidence suggests that indoxyl sulfate and p-cresyl...
作者:Lutgarde Thijs , Nigel Beckett ...
来源:[J].BMC Medicine(IF 6.679), 2015, Vol.13 (1)Springer
摘要:Abstract(#br) Background(#br)Treatment for hypertension with antihypertensive medication has been shown to reduce stroke, cardiovascular events, and mortality in older adults, but there is concern that such treatment may not be appropriate in frailer older adults. To investi...

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