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作者:Lucy Dorey , Peter Lees
来源:[J].BMC Veterinary Research(IF 1.861), 2017, Vol.13 (1)Springer
摘要:The most widely used measure of potency of antimicrobial drugs is Minimum Inhibitory Concentration (MIC). MIC is usually determined under standardised conditions in broths formulated to optimise bacterial growth on a species-by-species basis. This ensures comparability of data be...
作者:Lucy Dorey , Ludovic Pelligand , Peter Lees
来源:[J].BMC Veterinary Research(IF 1.861), 2017, Vol.13 (1)Springer
摘要:Bacterial pneumonia in pigs occurs widely and requires antimicrobial therapy. It is commonly caused by the pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida . Marbofloxacin is an antimicrobial drug of the fluoroquinolone class, licensed for use against these org...
作者:Lucy Dorey , Ludovic Pelligand ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (5)PLOS
摘要:Pharmacokinetic-pharmacodynamic (PK/PD) integration and modelling were used to predict dosage schedules for florfenicol for two pig pneumonia pathogens, Actinobacillus pleuropneumoniae and Pasteurella multocida . Pharmacokinetic data were pooled for two bioequivalent products, pi...

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