全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Erika Cristaldi , Giulia Romano , Lucia Malaguarnera
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2012, Vol.8 (4), pp.520-527DOAJ
摘要:Immunosenescence is the aging process involving the immune system competencies. These changes imply a reduced level of immunosurveillance against cancer onset and the occurrence of autoimmune phenomena. The clinical presentation of autoimmune diseases in the elderly is characteri...
作者:Lucia Malaguarnera , Lidia Puzzo ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2016, Vol.17 (3)DOAJ
摘要:Osteoarthritis is the most common human arthritis characterized by degeneration of articular cartilage. Several studies reported that levels of human cartilage glycoprotein chitinase 3-like-1 (CHI3L1) are known as a potential marker for the activation of chondrocytes and the...
作者:Lucia Malaguarnera , Giuseppe Nunnari , Michelino Di Rosa
来源:[J].Inflammation Research(IF 1.964), 2016, Vol.65 (11), pp.895-904Springer
摘要:Abstract(#br) Objective(#br)The OAS proteins are characterized by their capacity to synthesize 2′,5′-linked phosphodiester bonds to polymerize ATP into oligomers of adenosine. OAS3, belonging to OASs gene family, synthesizes dimeric 2-5A that binds to RNase L with low affini...
作者:... Antonio Zanghì , Antonino Passaniti , Lucia Malaguarnera
来源:[J].Critical Reviews in Oncology / Hematology(IF 4.637), 2013, Vol.88 (3), pp.594-612Elsevier
摘要:Abstract(#br)Traditionally the main recognized function of vitamin D has been calcium and phosphate homeostasis. Nevertheless, recent evidences have highlighted the importance of vitamin D3 as a protective agent against various cancers. The association between CRC and vitami...
作者:... Corinne Gregorio , Ferdinando Nicoletti , Lucia Malaguarnera
来源:[J].Inflammation Research(IF 1.964), 2012, Vol.61 (10), pp.1131-1139Springer
摘要:Abstract(#br) Objective(#br)To evaluate the heat shock protein (HSP) variation during the differentiation and polarization of human macrophages.(#br) Methods(#br)Gene expression analysis was investigated by real-time PCR from mRNA of human monocytes obtained from the buffy coats ...
作者:Lucia Malaguarnera , Sergio Castorina ...
来源:[J].Molecular Neurobiology(IF 5.471), 2018, Vol.55 (8), pp.6881-6893Springer
摘要:Abstract(#br)Fasting may be exploited as a possible strategy for prevention and treatment of several diseases such as diabetes, obesity, and aging. On the other hand, high-fat diet (HFD) represents a risk factor for several diseases and increased mortality. The aim of the present...
作者:Lucia Malaguarnera , Erika Cristaldi , Mariano Malaguarnera
来源:[J].Critical Reviews in Oncology and Hematology(IF 4.637), 2009, Vol.74 (1), pp.40-60Elsevier
摘要:Abstract(#br)The increased incidence of malignancies in elderly patients living in industrialized countries has led to both identify the causes that alter the normal homeostatic balance in elderly and designate the specific treatments. The progressive decline of the immune system...
作者:... Maria Sofia Basile , Francesco Di Raimondo , Lucia Malaguarnera
来源:[J].Immunobiology(IF 2.814), 2016, Vol.221 (2), pp.347-356Elsevier
摘要:Abstract(#br)Chitinase-3-like-1 protein (CHI3L1) is a glycosyl hydrolase (GH) highly expressed in a variety of inflammatory diseases at infectious and non-infectious etiology. CHI3L1 is produced by a wide variety of cells including monocyte-derived macrophages cell lines such as ...
作者:... Gisella Distefano , Katarzyna Zorena , Lucia Malaguarnera
来源:[J].Immunobiology(IF 2.814), 2016, Vol.221 (3), pp.399-411Elsevier
摘要:Abstract(#br)Chitinases belonging to 18 glycosyl hydrolase family is an ancient gene family that is widely expressed from prokaryotes to eukaryotes. In humans, despite the absence of endogenous chitin, a number of Chitinases and Chitinase-like Proteins (C/CLPs) have been identifi...
作者:... Massimo Libra , Giuseppe Musumeci , Lucia Malaguarnera
来源:[J].Acta Histochemica(IF 1.608), 2015, Vol.117 (4-5), pp.477-485Elsevier
摘要:Abstract(#br)Malignant brain tumors are the most common pediatric solid tumors and are the leading cause of death from childhood cancers. These tumors include several histologic subtypes. Due to the particular properties of brain tumors, such as growth and division, examination o...

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