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作者:Lorena Citterio , Simona Delli Carpini ...
来源:[J].BMC Medical Genetics(IF 2.536), 2017, Vol.18 (1)Springer
摘要:Platelet Endothelial Aggregation Receptor 1 (PEAR1), a membrane protein highly expressed in platelets and endothelial cells, plays a role in platelet contact-induced activation, sustained platelet aggregation and endothelial function. Previous reports implicate PEAR1 rs12041331 a...
作者:Lorena Citterio , Simona Delli Carpini ...
来源:[J].BMC Genetics(IF 2.808), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)In mice MEOX2/TCF15 heterodimers are highly expressed in heart endothelial cells and are involved in the transcriptional regulation of lipid transport. In a general population, we investigated whether genetic variation in these genes predicted co...
作者:Lorena Citterio , Marco Simonini ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.6 (5)DOAJ
摘要:The importance of excess salt intake in the pathogenesis of hypertension is widely recognized. Blood pressure is controlled primarily by salt and water balance because of the infinite gain property of the kidney to rapidly eliminate excess fluid and salt. Up to fifty percent of p...
作者:Lorena Citterio , Roberta Meroni ...
来源:[J].American Journal of Kidney Diseases(IF 5.294), 2019, Vol.73 (4), pp.504-512Elsevier
摘要:Rationale & Objective(#br)Studies of humans and animals have suggested that endogenous ouabain (EO) and related genes are mediators of acute (AKI) and chronic kidney injury. We sought to examine the relationship among EO levels, genetic variants in lanosterol synthase (LSS; ...
作者:Lorena Citterio , Claudia Cassandro ...
来源:[J].European Archives of Oto-Rhino-Laryngology(IF 1.458), 2017, Vol.274 (2), pp.757-763Springer
摘要:Abstract(#br)Aim of this work was to assess the role of polymorphisms belonging to genes involved in the regulation of ionic homeostasis in Caucasian patients with Ménière Disease (MD). We recruited 155 patients with definite Ménière Disease and 186 controls (Control Group 1...
作者:Lorena Citterio , Simona Delli Carpini ...
来源:[J].Journal of Neuroimmunology(IF 3.033), 2018Elsevier
摘要:Abstract(#br)Patients with systemic lupus erythematosus (SLE) carrying a TT genotype for the rs7925662 single nucleotide polymorphism (SNP) in the transient receptor potential canonical channel 6 (TRPC6) gene are more likely to develop neuropsychiatric manifestations (NPSLE). We ...
作者:Lorena Citterio , Laura Zagato ...
来源:[J].Journal of Neuroimmunology(IF 3.033), 2015, Vol.288, pp.21-24Elsevier
摘要:Abstract(#br)Neuropsychiatric manifestations of systemic lupus erythematosus (NPSLE) influence patients' quality of life and their survival. Little is known about the pathophysiological bases of NPSLE and accordingly there are no specific therapeutic agents to be employed in this...
作者:Lorena Citterio , Nunzia Casamassima ...
来源:[J].Rheumatology International(IF 2.214), 2015, Vol.35 (12), pp.1975-1983Springer
摘要:Abstract(#br)Genetic research in systemic lupus erythematosus (SLE) is rapidly developing, and numerous sets of genes are being associated with specific clinical subphenotypes in the setting of SLE. On the other hand, basic science studies are revealing strong connections be...
作者:Lorena Citterio , Chiara Lanzani ...
来源:[J].BBA - Molecular Basis of Disease(IF 4.91), 2010, Vol.1802 (12), pp.1285-1298Elsevier
摘要:Abstract(#br)The usefulness of the results so far published on genetics of primary hypertension for establishing the clinical impact of candidate gene polymorphisms is weakened by the scanty information regarding: a) the functional effect of the gene variants of interest in ...

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