全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Linhong Zhao , Xing Huang
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:Nanobodies are single-domain antibodies that contain the unique structural and functional properties of naturally-occurring heavy chain in camelidae. As a novel class of antibody, they show many advantages compared with traditional antibodies such as smaller size, higher stabilit...
作者:Linhong Zhao , Yang Yang ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (10)DOAJ
摘要:Histone post-translational modification heritably regulates gene expression involved in most cellular biological processes. Experimental studies suggest that alteration of histone modifications affects gene expression by changing chromatin structure, causing various cellular resp...
作者:Linhong Zhao , Yao Zhao ...
来源:[J].Journal of Inorganic Biochemistry(IF 3.197), 2016, Vol.161, pp.99-106Elsevier
摘要:Abstract(#br)Herein we report investigation of the interactions between anticancer organoruthenium complexes, [(η 6 -arene)Ru(en)(Cl)]PF 6 (en = ethylenediamine, arene = p -cymene ( 1 ) or biphenyl ( 2 )), and the human copper chaperone protein Cox17 by mass spectrometry wi...
作者:Linhong Zhao , Zekun Liu ...
来源:[J].Frontiers in Genetics, 2019, Vol.10DOAJ
摘要:As a widespread post-translational modification of proteins, calpain-mediated cleavage regulates a broad range of cellular processes, including proliferation, differentiation, cytoskeletal reorganization, and apoptosis. The identification of proteins that undergo calpain cleavage...
作者:Linhong Zhao , Junaid Ali Shah ...
来源:[J].Molecules(IF 2.428), 2018, Vol.23 (8)MDPI
摘要:As one of the post-translational modifications, O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) often occurs on serine (Ser) and threonine (Thr) residues of specific substrate cellular proteins via the addition of O-GlcNAc group by O-GlcNAc transfera...
作者:Linhong Zhao , Xue Yu ...
来源:[J].International Journal of Oncology(IF 2.657), 2015, Vol.46 (6), pp.2535-2545Spandidos
摘要:Increasing evidence suggests that the alteration of global histone H4K16acetylation (H4K16ac) may be involved in several types of cancer. It is knownthat the global histone H4K16ac level in cells is controlled by several enzymesincluding histone acetyltransferases (HATs) and hist...
作者:Linhong Zhao , Yang Yang ...
来源:[J].PLOS ONE(IF 3.73), 2015, Vol.10 (10)PLOS
摘要:Histone post-translational modification heritably regulates gene expression involved in most cellular biological processes. Experimental studies suggest that alteration of histone modifications affects gene expression by changing chromatin structure, causing various cellular resp...
作者:Linhong Zhao , Zhen Wang ...
来源:[J].Biochemical Journal(IF 4.654), 2015, Vol.472 (2), pp.217-223Duke University Press
摘要:GSH enhances the reactivity of cisplatin to cytochrome c oxidase copper chaperone (Cox17), but suppresses the reaction of transplatin. The cisplatin-GSH adducts are highly reactive to Cox17; over 90% platinum forms Cox17 adducts. On the contrary, transplatin-GSH adducts are ...

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