| 作者：Leo Lai Chan , Paul Kwan Sing Lam |
| 来源：[J].Molecular Neurobiology(IF 5.471), 2017, Vol.54 (7), pp.5590-5603Springer |
| 摘要：Ciguatera fish poisoning (CFP) is a common human food poisoning caused by consumption of ciguatoxin (CTX)-contaminated fish affecting over 50,000 people worldwide each year. CTXs are classified depending on their origin from the Pacific (P-CTXs), Indian Ocean (I-CTXs), and C... |
全文获取| 作者：Leo Lai Chan , Paul Kwan Sing Lam |
| 来源：[J].Molecular Neurobiology(IF 5.471), 2018, Vol.55 (8), pp.6769-6787Springer |
| 摘要：Abstract(#br)Consumption of fish containing ciguatera toxins or ciguatoxins (CTXs) causes ciguatera fish poisoning (CFP). In some patients, CFP recurrence occurs even years after exposure related to CTXs accumulation. Pacific CTX-1 (P-CTX-1) is one of the most potent natural subs... |
| 作者：... Donald M. Anderson , Leo Lai Chan , Michael L. Berumen |
| 来源：[J].Harmful Algae(IF 2.901), 2017, Vol.68, pp.206-216Elsevier |
| 摘要：Abstract(#br)This study confirms the presence of the toxigenic benthic dinoflagellates Gambierdiscus belizeanus and Ostreopsis spp. in the central Red Sea. To our knowledge, this is also the first report of these taxa in coastal waters of Saudi Arabia, indicating the potenti... |
| 作者：... Paul Kwan Sing Lam , Leo Lai Chan , Mingfu Wang |
| 来源：[J].Toxicon(IF 2.924), 2014, Vol.77, pp.16-25Elsevier |
| 摘要：Abstract(#br)Saxitoxin (STX) is the most potent paralytic shellfish poisoning toxin in crustaceans and molluscs, and is known to cause intoxication to humans and marine animals due to its neurotoxicity. However, the extent of its early developmental toxicity to marine species rem... |
| 作者：Leo Lai Chan , Aranteiti Tekiau |
| 来源：[J].Harmful Algae(IF 2.901), 2014, Vol.34, pp.56-68Elsevier |
| 摘要：Abstract(#br)Ciguatera is a serious seafood poisoning syndrome caused by the consumption of ciguatoxin-contaminated finfish from tropical and subtropical regions. This study examined the community structure of ciguatera-associated dinoflagellates and the distribution pattern... |
| 作者：Leo Lai Chan , Paul Kwan Sing Lam |
| 来源：[J].Ecotoxicology(IF 2.773), 2015, Vol.24 (7-8), pp.1744-1753Springer |
| 摘要：Abstract(#br)Paralytic shellfish toxins (PSTs) are originated from cyanobacteria and dinoflagellates, including Alexandrium tamarense , the common dinoflagellate species. In this study, a toxic dinoflagellate strain of A . tamarense CI01 was selected for studying the PSTs’ c... |
| 作者：Leo Lai Chan , Paul Kwan Sing Lam |
| 来源：[J].Ecotoxicology(IF 2.773), 2015, Vol.24 (6), pp.1395-1406Springer |
| 摘要：Abstract(#br)Three methods for extraction and preparation of high-quality proteins from both toxic and non-toxic dinoflagellates for proteomics analysis, including Trizol method, Lysis method and Tris method, were compared with the subsequent protein separation profiles using 2-D... |
| 作者：Leo Lai Chan , Xiaomin Li ... |
| 来源：[J].Harmful Algae(IF 2.901), 2012, Vol.16, pp.58-62Elsevier |
| 摘要：Abstract(#br)Revealing the profile of dinoflagellate cell surface proteins (CSPs) is a crucial step for developing molecular probes for effective identification, separation and enumeration of toxic and non-toxic dinoflagellates. This study aimed to develop theca-specific antibodi... |