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作者:Leah W. Roberts , Mitchell Stanton-Cook ...
来源:[J].mBio(IF 5.621), 2016, Vol.7 (2)
摘要:Escherichia coli ST131 is the most frequently isolated fluoroquinolone-resistant (FQR) E. coli clone worldwide and a major cause of urinary tract and bloodstream infections. Although originally identified through its association with the CTX-M-15 extended-spectrum β-lactamas...
作者:Leah W. Roberts , Minh‐Duy Phan ...
来源:[J].Molecular Microbiology(IF 4.961), 2016, Vol.101 (6), pp.1069-1087
摘要:Summary(#br)Uropathogenic Escherichia coli (UPEC) of sequence type 131 (ST131) are a pandemic multidrug resistant clone associated with urinary tract and bloodstream infections. Type 1 fimbriae, a major UPEC virulence factor, are essential for ST131 bladder colonization. The...
作者:Leah W. Roberts , Patrick N. A. Harris ...
来源:[J].Nature Communications(IF 10.015), 2020, Vol.11 (1), pp.657-686
摘要:Abstract(#br)Carbapenem-resistant Enterobacteriaceae (CRE) represent an urgent threat to human health. Here we report the application of several complementary whole-genome sequencing (WGS) technologies to characterise a hospital outbreak of bla IMP-4 carbapenemase-prod...
作者:Leah W. Roberts , Minh-Duy Phan ...
来源:[J].Nature Communications(IF 10.015), 2019, Vol.10 (1), pp.269-284
摘要:Abstract(#br)Recurrent urinary tract infections (rUTIs) are extremely common, with ~ 25% of all women experiencing a recurrence within 1 year of their original infection. Escherichia coli ST131 is a globally dominant multidrug resistant clone associated with high rates of rUTI. H...
作者:Leah W. Roberts , Mathew Upton ...
来源:[J].Journal of Antimicrobial Chemotherapy(IF 5.338), 2015, Vol.70 (7), pp.1969-1972
摘要:ObjectivesEscherichia coli ST131 is a globally disseminated MDR clone originally identified due to its association with the blaCTX-M-15 gene encoding an ESBL. It is thus assumed that blaCTX-M-15 is the major determinant for resistance to β-lactam antibiotics in this clone. T...
作者:Leah W. Roberts , Elizabeth Catchpoole ...
来源:[J].Microbial Genomics, 2019
摘要:Carbapenemase-producing Enterobacteriaceae (CPE) are an increasingly common cause of healthcare-associated infections and may occasionally be identified in patients without extensive healthcare exposure. bla IMP-4 is the most frequently detected carbapenemase gene...

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