全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Laurent Grange , Françoise Morel
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (6)DOAJ
摘要:Interleukin-1β (IL-1β) activates the production of reactive oxygen species (ROS) and secretion of MMPs as well as chondrocyte apoptosis. Those events lead to matrix breakdown and are key features of osteoarthritis (OA). We confirmed that in human C-20/A4 chondrocytes the NAD...
作者:... Bernard Lardy , Laurent Grange , Thierry Conrozier
来源:[J].Polymers(IF 1.687), 2014, Vol.6 (7), pp.1948-1957DOAJ
摘要:In this paper, we propose the evaluation of the mannitol’s ability to reduce hyaluronic acid (HA) degradation using two different models of oxidative stress. Firstly, a solution of hyaluronan and a solution of the same HA including mannitol in PBS buffer were submitted to an...
作者:Laurent Grange , Bertrand Toussaint ...
来源:[J].Joint Bone Spine(IF 2.748), 2018Elsevier
摘要:Abstract(#br)Objectives(#br)Tumour necrosis factor-alpha inhibitors (TNFi) are effective treatments for Rheumatoid Arthritis (RA). Responses to treatment are barely predictable. As these treatments are costly and may induce a number of side effects, we aimed at identifying a...
作者:Laurent Grange , Gérard Thibaud ...
来源:[J].Joint Bone Spine(IF 2.748), 2019Elsevier
摘要:Abstract(#br)Objectives:a) to describe the self-reported adherence to disease modifying drugs (DMARDs) (methotrexate and biological DMARDs) among patients with chronic inflammatory rheumatic diseases (CIRDs); b) to assess factors associated with non-adherence.(#br)Methods:An...
作者:Laurent Grange , Félicie Costantino ...
来源:[J].Joint Bone Spine(IF 2.748), 2019Elsevier
摘要:Abstract(#br)Objective(#br)Information and education are recommended for patients with inflammatory arthritis including rheumatoid arthritis (RA) and spondyloarthritis (SpA). However, there is no consensus on which knowledge is essential to enhance patients’ self-management....
作者:Laurent Grange , Cécile Hacquard-Bouder ...
来源:[J].Revue d'Epidemiologie et de Santé Publique(IF 0.686), 2016, Vol.64, pp.S281-S282Elsevier
摘要:Objectifs(#br)Évaluer la concordance entre évaluation clinique (C) et échographie (ultrason–US) de la synovite (modes B, D et B + D) dans la polyarthrite rhumatoïde (PR) active avant et après traitement par anti-TNF, puis étudier les facteurs associés à une bonne c...
作者:Laurent Grange , Catherine Beauvais ...
来源:[J].Joint Bone Spine(IF 2.748), 2017Elsevier
摘要:Abstract(#br)Introduction(#br)Sanoia is an online interactive electronic e-health platform developed to allow patient self-assessment and self-monitoring. The objective was to assess in rheumatoid arthritis (RA) patients, the efficacy on patient-physician interactions, of gi...
作者:Laurent Grange , Marie Caroline Guzian ...
来源:[J].Joint Bone Spine(IF 2.748), 2012, Vol.79 (6), pp.586-590Elsevier
摘要:Abstract(#br)Power Doppler ultrasound (PDUS) has proved to be a highly sensitive tool for assessing enthesitis in spondyloarthritis (SpA). In patients with a suspected SpA, diagnosis could be improved by detecting enthesitis with PDUS.(#br)Objective(#br)To evaluate the perfo...

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