全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Kyoko Tsukiyama-Kohara , Yoshitsugu Matsumoto ...
来源:[J].PLoS Neglected Tropical Diseases(IF 4.716), 2017, Vol.9 (7)DOAJ
摘要:Canine distemper virus (CDV) vaccination confers long-term protection against CDV reinfection. To investigate the utility of CDV as a polyvalent vaccine vector for Leishmania, we generated recombinant CDVs, based on an avirulent Yanaka strain, that expressed Leishmania antigens: ...
作者:... Tomohiro Nishimura , Michinori Kohara , Kyoko Tsukiyama-Kohara
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (4)DOAJ
摘要:In our previous study, we demonstrated that 3β-hydroxysterol Δ24-reductase (DHCR24) was overexpressed in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), and that its expression was induced by HCV. Using a monoclonal antibody against DHCR24 (2-152a MAb), we fo...
作者:Kyoko Tsukiyama-Kohara , Takaji Wakita ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (12)DOAJ
摘要:Chronic hepatitis C, which is caused by infection with the hepatitis C virus (HCV), is a global health problem. Using a mouse model of hepatitis C, we examined the therapeutic effects of a recombinant vaccinia virus (rVV) that encodes an HCV protein. We generated immunocompe...
作者:Khadija Rebbani , Kyoko Tsukiyama-Kohara , Maria G. Isaguliants
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2016, Vol.2016Hindawi
摘要:About 150 million people worldwide are chronically infected with hepatitis C virus (HCV). The persistence of the infection is controlled by several mechanisms including the induction of oxidative stress. HCV relies on this strategy to redirect lipid metabolism machinery and ...
作者:Bouchra Kitab , Michinori Kohara , Kyoko Tsukiyama-Kohara
来源:[J].Archives of Virology(IF 2.03), 2018, Vol.163 (7), pp.1717-1726Springer
摘要:Abstract(#br)Dengue is the most prevalent arboviral disease in humans and leads to significant morbidity and socioeconomic burden in tropical and subtropical areas. Dengue is caused by infection with any of the four closely related serotypes of dengue virus (DENV1-4) and usu...
作者:... Tatsuya Kasahara , Yusuke Amano , Kyoko Tsukiyama-Kohara
来源:[J].Archives of Virology(IF 2.03), 2019, Vol.164 (11), pp.2735-2745Springer
摘要:Abstract(#br)Koala retrovirus (KoRV) is unique among endogenous retroviruses because its endogenization is still active. Two major KoRV subtypes, KoRV-A and B, have been described, and KoRV-B is associated with disease and poses a health threat to koalas. Here, we investigated th...
作者:Kyoko Tsukiyama-Kohara , Naoki Yamamoto ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2016, Vol.469 (2), pp.229-235Elsevier
摘要:Abstract(#br)The northern treeshrew ( Tupaia belangeri ) has been reported to be an effective candidate for animal infection model with hepatitis B virus (HBV). The objective of our study was to analyze the growth characteristics of HBV in tupaia hepatocytes and the host res...
作者:... Tatsunori Masatani , Makoto Ozawa , Kyoko Tsukiyama-Kohara
来源:[J].Veterinary Microbiology(IF 3.127), 2015, Vol.179 (3-4), pp.219-227Elsevier
摘要:Abstract(#br)Non-primate hepacivirus (NPHV) is a recently discovered homolog of the hepatitis C virus in horses. The frequency and distribution of NPHV infections among horses in Japan is unknown. In this study, serum samples from 453 horses across Japan were screened for NP...

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