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作者:Kung H.-J. , Chen H.-C. , Robinson D.
来源:[J].Journal of Biomedical Science(IF 2.458), 1998, Vol.5 (2), pp.74-78Karger
摘要:As the post-genome era is approaching, with vast amount of sequence information available and new technology developed, scientists are presented with opportunities to explore in simple analysis the structure and expression pattern of not just a single gene, but of an entire ...
作者:Chen H.-Ch. , Kung H.-J. , Robinson D.
来源:[J].Journal of Biomedical Science(IF 2.458), 1998, Vol.5 (2), pp.86-92Karger
摘要:Identification of novel kinases based on their sequence conservation within kinase catalytic domain has relied so far on two major approaches, low-stringency hybridization of cDNA libraries, and PCR method using degenerate primers. Both of these approaches at times are technicall...
作者:... Lin W.-Ch. , Hayman M.J. , Kung H.-J.
来源:[J].Journal of Biomedical Science(IF 2.458), 1998, Vol.5 (2), pp.93-100Karger
摘要:Tyrosine kinases are implicated in the growth and differentiation of erythroid cells. Aberrant expression and structural alterations of certain tyrosine kinases, such as erbB and sea, are known to trigger erythroleukemia development. To facilitate our understanding of the si...
作者:Kung H.-J. , Chi C.-W. ...
来源:[J].Journal of Biomedical Science(IF 2.458), 1998, Vol.5 (2), pp.101-110Karger
摘要:Protein kinases play key roles in cellular functions. They are involved in many cellular functions including; signal transduction, cell cycle regulation, cell division, and cell differentiation. Alterations of protein kinase by gene amplification, mutation or viral factors often ...

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