全部文献期刊会议图书|学者科研项目
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作者:Kristina Lorenz , Georg Ertl
来源:[J].BMC Cardiovascular Disorders(IF 1.457), 2017, Vol.17 (1)
摘要:Aortic valve stenosis is a common finding diagnosed with high sensitivity in transthoracic echocardiography, but the examiner often finds himself confronted with uncertain results in patients with moderate pressure gradients and concomitant systolic heart failure. While patients ...
作者:Kristina Lorenz , Maria Cybularz ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (3)
摘要:Estrogen modulates adrenergic reactivity of macrovessels, resulting in weaker α-adrenergic vasoconstriction in females than males. However, the mechanisms governing this important sex-specific difference are not well understood. We hypothesized that vessels of females expres...
作者:... Cornelius Krasel , Moritz Bünemann , Kristina Lorenz
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2019, Vol.520 (2), pp.327-332
摘要:Abstract(#br)The Raf kinase inhibitor protein (RKIP) activates β-adrenoceptors (β-AR) and thereby induces a well-tolerated cardiac contractility and prevents heart failure in mice. Different to RKIP-mediated β-AR activation, chronic activation of β-AR by catecholamines was s...
作者:Kristina Lorenz , Albert Sickmann
来源:[J].BBA - Molecular and Cell Biology of Lipids(IF 4.134), 2017, Vol.1862 (8), pp.808-811
摘要:Abstract(#br)During the past decades, high-throughput approaches for analyzing different molecular classes such as nucleic acids, proteins, metabolites, and lipids have grown rapidly. These approaches became powerful tools for getting a fundamental understanding of biological sys...
作者:... Ilka Wittig , Kristina Lorenz , Philip Eaton
来源:[J].Molecular Aspects of Medicine(IF 10.375), 2018
摘要:Abstract(#br)Oxidants are produced endogenously and can react with and thereby post-translationally modify target proteins. They have been implicated in the redox regulation of signal transduction pathways conferring protection, but also in mediating oxidative stress and causing ...
作者:Tim Breitenbach , Kristina Lorenz , Thomas Dandekar
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2019, Vol.20 (9)
摘要:Mathematical optimization framework allows the identification of certain nodes within a signaling network. In this work, we analyzed the complex extracellular-signal-regulated kinase 1 and 2 (ERK1/2) cascade in cardiomyocytes using the framework to find efficient adjustment screw...
作者:Kristina Lorenz , Georg Ertl
来源:[J].Journal of the American Society of Echocardiography(IF 4.277), 2015, Vol.28 (11), pp.1270-1282.e4
摘要:Background(#br)The aim of the present study was to assess and compare the disease progression of aortic stenosis (AS) subtypes from nonsevere to severe disease on the basis of measures of gradient and flow.(#br)Methods(#br)Seventy-seven patients with AS (mean aortic valve ar...

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