全部文献期刊会议图书|学者科研项目
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作者:... André Fisahn , Kjell Fuxe , Dasiel O. Borroto-Escuela
来源:[J].Neuropharmacology(IF 4.114), 2020
摘要:Abstract(#br)The majority of the fibroblast growth factor receptor 1-serotonin 1 A receptor (FGFR1-5-HT1AR) heterocomplexes in the hippocampus appeared to be located mainly in the neuronal networks and a relevant target for antidepressant drugs. Through a neurochemical and electr...
作者:... José Rejon-Orantes , Dasiel O. Borroto-Escuela , Kjell Fuxe
来源:[J].Neuroscience(IF 3.122), 2019
摘要:Abstract(#br)The dopaminergic system integrated by cell groups distributed in several brain regions exerts a modulatory role in brain. Particularly important for this task are the mesencephalic dopamine neurons, which from the substantia nigra and ventral tegmental area proj...
作者:Kjell Fuxe , Luis Santín
来源:[J].Neuropharmacology(IF 4.114), 2017, Vol.118, pp.233-241
摘要:Abstract(#br)The pharmacological treatment of major depression is mainly based on drugs elevating serotonergic (5-HT) activity. Specifically, selective 5-HT reuptake inhibitors, including Fluoxetine (FLX), are the most commonly used for treatment of major depression. However...
作者:... Anna Sadakierska-Chudy , Michael Bader , Kjell Fuxe
来源:[J].Neuroscience(IF 3.122), 2019, Vol.418, pp.133-148
摘要:Abstract(#br)Preclinical data indicate that ethanol produces behavioral effects that can be regulated by many neurotransmitters and neuromodulators like adenosine (A). The most important receptors with respect to the rewarding effects of ethanol seem to be the A 2A receptors. Thi...
作者:... Carlos A. Saura , Kjell Fuxe , Rafael Franco
来源:[J].Brain Behavior and Immunity(IF 5.612), 2018, Vol.67, pp.139-151
摘要:Abstract(#br)Endocannabinoids are important regulators of neurotransmission and, acting on activated microglia, they are postulated as neuroprotective agents. Endocannabinoid action is mediated by CB 1 and CB 2 receptors, which may form heteromeric complexes (CB 1 -CB 2 Hets...
作者:... Sergio Tanganelli , Kjell Fuxe , Luca Ferraro
来源:[J].Cellular Signalling(IF 4.304), 2017, Vol.40, pp.116-124
摘要:Abstract(#br)The effects of nanomolar cocaine concentrations, possibly not blocking the dopamine transporter activity, on striatal D 2 -σ 1 heteroreceptor complexes and their inhibitory signaling over Gi/o, have been tested in rat striatal synaptosomes and HEK293T cells. Fur...
作者:... Karolina Wydra , Malgorzata Filip , Kjell Fuxe
来源:[J].Trends in Pharmacological Sciences(IF 9.25), 2018
摘要:The concept of allosteric receptor–receptor interactions in G protein-coupled receptor homo- and heteroreceptor complexes in which they physically interact provides a new dimension to molecular integration in the brain. The receptor–receptor interactions dynamically change r...

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