全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Akiko Ota , Taku Nagai , Kiyofumi Yamada
来源:[J].International Journal of Clinical Oncology(IF 1.727), 2017, Vol.22 (3), pp.593-599Springer
摘要:Nedaplatin (NDP)-related hypersensitivity reactions (HSRs) trigger adverse clinical events. Prediction and prevention of NDP-HSRs are thus essential to minimize the risk and maximize the benefit of NDP therapy. However, the incidence of NDP-HSRs and the associated risk factors re...
作者:Kiyofumi Yamada , Toshitaka Nabeshima
来源:[J].Archives of Pharmacal Research(IF 1.538), 2017, Vol.40 (4), pp.403-428Springer
摘要:Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is associated with extensive neurodegeneration, psychosis, and cognitive impairment. Evidence from animal models has suggested a considerable role of excess dopamine or glutamate, oxidative...
作者:Kiyofumi Yamada , Toshitaka Nabeshima
来源:[J].Molecular Neurobiology(IF 5.471), 2017, Vol.54 (9), pp.7042-7062Springer
摘要:Escalating evidence suggests that the impairment of glutathione (GSH)-dependent systems is one of the etiologic factors of schizophrenia. GSH is an important substrate of glutathione peroxidase (GPx). Among GPx isozymes, selenium-dependent GPx (GPx-1) is recognized as a majo...
作者:Kiyofumi Yamada , Toshitaka Nabeshima
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2016, Vol.132 (2), pp.166-170Elsevier
摘要:Abstract(#br)Dextromethorphan (DM) administered at supra-antitussive doses produce psychotoxic and neurotoxic effects in humans. We administered DM (80 mg/kg) to rats intraperitoneally to determine the ultrastructural change induced by DM, because intraperitoneal route is sensiti...
作者:Kiyofumi Yamada , Toshitaka Nabeshima
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2016, Vol.132 (2), pp.166-170DOAJ
摘要:Dextromethorphan (DM) administered at supra-antitussive doses produce psychotoxic and neurotoxic effects in humans. We administered DM (80 mg/kg) to rats intraperitoneally to determine the ultrastructural change induced by DM, because intraperitoneal route is sensitive for the be...
作者:Kiyofumi Yamada , Satoru Miyano ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (12)DOAJ
摘要:Juvenile myelomonocytic leukemia (JMML), an overlap of myelodysplastic / myeloproliferative neoplasm, is an intractable pediatric myeloid neoplasm. Epigenetic regulation of transcription, particularly by CpG methylation, plays an important role in tumor progression, mainly by rep...
作者:... Kenji Sakimura , Kiyofumi Yamada , Mikio Hoshino
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (12)DOAJ
摘要:Mutations in the Autism susceptibility candidate 2 gene (AUTS2) have been associated with a broad range of psychiatric illnesses including autism spectrum disorders, intellectual disability and schizophrenia. We previously demonstrated that the cytoplasmic AUTS2 acts as an upstre...
作者:Daisuke Ibi , Kiyofumi Yamada
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2015, Vol.16 (12), pp.28218-28229DOAJ
摘要:Increasing epidemiological evidence indicates that perinatal infection with various viral pathogens enhances the risk for several psychiatric disorders. The pathophysiological significance of astrocyte interactions with neurons and/or gut microbiomes has been reported in neurodev...
作者:... Daisuke Ibi , Akira Nakajima , Kiyofumi Yamada
来源:[J].Brain Behavior and Immunity(IF 5.612), 2014, Vol.38, pp.272-282Elsevier
摘要:Abstract(#br)Increasing epidemiological evidence indicates that prenatal infection and childhood central nervous system infection with various viral pathogens enhance the risk for several neuropsychiatric disorders. Polyriboinosinic–polyribocytidilic acid (polyI:C) is known ...
作者:Kiyofumi Yamada , Yukiko Enomoto ...
来源:[J].Annals of Vascular Surgery(IF 0.985), 2012, Vol.26 (5), pp.731.e9-731.e13Elsevier
摘要:The authors report a novel stepwise carotid revascularization method to prevent perioperative complication. A 68-year-old man presented with left hemiparesis and dysarthria caused by severe stenosis of the right cervical internal carotid artery. According to the preoperative cere...

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