全部文献期刊会议图书|学者科研项目
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作者:Kim de Jong , Xijin Xu ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Respiratory symptoms are associated with accelerated lung function decline, and increased hospitalization and mortality rates in the general population. Although several environmental risk factors for respiratory symptoms are known, knowledge on genetic risk factors is lacking. W...
作者:Kim de Jong , Judith M. Vonk ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:It has been observed that mice lacking the sulfatase modifying factor ( Sumf1 ) developed an emphysema-like phenotype. However, it is unknown if SUMF1 may play a role in Chronic Obstructive Pulmonary Disease (COPD) in humans. The aim was to investigate if the expression and genet...
作者:... Wilco H. M. Emons , Kim de Jong , Klaas Sijtsma
来源:[J].Quality of Life Research(IF 2.412), 2017, Vol.26 (6), pp.1473-1481
摘要:In the absence of measurement invariance across measurement occasions, change scores based on pretest–posttest measurements may be inaccurate representations of real change on the latent variable. In this study, we examined whether measurement invariance held in the Dutch ve...
作者:... Xia Huo , Kim de Jong , H. Marike Boezen
来源:[J].Environment International(IF 6.248), 2019, Vol.122, pp.263-269
摘要:Abstract(#br)Respiratory symptoms are important indicators of respiratory diseases. Both genetic and environmental factors contribute to respiratory symptoms development but less is known about gene-environment interactions. We aimed to assess interactions between single nuc...
作者:Kim De Jong , Niels A. Noordzij ...
来源:[J].European Journal of Surgical Oncology(IF 2.614), 2018, Vol.44 (1), pp.157-162
摘要:Abstract(#br)Background(#br)Basal cell carcinomas (BCCs) excised leaving positive tumour margins, are at a higher risk of recurrence. Accordingly, complete tumour removal with preservation of healthy tissue, aiming for low recurrence rates, is the main goal in treating BCCs....
作者:Kim de Jong , Judith M. Vonk ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2015, Vol.136 (6), pp.1664-1672.e14
摘要:Background(#br)Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by impaired lung function and airway obstruction resulting from interactions between multiple genes and multiple environmental exposures. Thus far, genome-wide association studies have ...
作者:Kim de Jong , Emilie Stroh ...
来源:[J].PLoS Neglected Tropical Diseases(IF 4.569), 2017, Vol.4 (11)
摘要:BACKGROUND: Snakebites are a public health problem in Nicaragua: it is a tropical developing country, venomous snakes are present and there are reports of snakebites treated both in the formal and informal health care system. We aimed to produce an incidence map using data report...
作者:Kim de Jong , Terri H Beaty ...
来源:[J].PLoS Genetics(IF 8.694), 2019, Vol.15 (7)
摘要:While many disease-associated single nucleotide polymorphisms (SNPs) are associated with gene expression (expression quantitative trait loci, eQTLs), a large proportion of complex disease genome-wide association study (GWAS) variants are of unknown function. Some of these SNPs ma...
作者:Kim de Jong , Lies Lahousse ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2016
摘要:Background(#br)Although a striking proportion (25% to 45%) of patients with chronic obstructive pulmonary disease are never-smokers, most genetic susceptibility studies have not focused on this group exclusively.(#br)Objective(#br)The aim of this study was to identify common...

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