全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Cheng Wang , Kejing Song , Jianping Wen
来源:[J].Microbial Cell Factories(IF 3.306), 2017, Vol.16 (1)Springer
摘要:Ascomycin is a 23-membered polyketide macrolide with high immunosuppressant and antifungal activity. As the lower production in bio-fermentation, global metabolic analysis is required to further explore its biosynthetic network and determine the key limiting steps for rationally ...
作者:Kejing Song , Liang Wei ...
来源:[J].Applied Microbiology and Biotechnology(IF 3.689), 2017, Vol.101 (11), pp.4581-4592Springer
摘要:Ascomycin (FK520), a macrocyclic polyketide natural antibiotic, displays high anti-fungal and immunosuppressive activity. In this study, the LysR family transcriptional regulator FkbR1 was characterized, and its role in ascomycin biosynthesis was explored by gene deletion, comple...
作者:Kejing Song , Grace A Maresh ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (9)DOAJ
摘要:BACKGROUND: In humans it has been reported that a major site of the latent reservoir of HIV is within CD4+ T cells expressing the memory marker CD45RO, defined by the mAb UCHL1. There are conflicting reports regarding the expression of this antigen in macaques, the most relevant ...
作者:Kejing Song , Grace A. Maresh ...
来源:[J].Toxins(IF 2.129), 2014, Vol.6 (5), pp.1512-1525DOAJ
摘要:We have studied the role of the antibody (Ab) Fc region in mediating protection from ricin toxicity. We compared the in vitro and in vivo effects of intact Ig and of Fab fragments derived from two different neutralizing Ab preparations, one monoclonal, the other polyclonal. ...
作者:Kejing Song , Hui Ma ...
来源:[J].Langmuir, 2013, Vol.29 (33), pp.10573鈥?0578ACS
摘要:In the past few years, scientists have paid increasing attention to many types of nanomaterials because of their potential in the design and fabrication of the next generation of agents for clinical purposes such as imaging, diagnosis, and therapy. ... It was observed that w...
作者:Kejing Song , Ruth A. Coleman ...
来源:[J].Alcohol(IF 2.255), 2001, Vol.24 (3), pp.155-167Elsevier
摘要:Abstract(#br)Patients with chronic inflammatory diseases, including Crohn's disease and rheumatoid arthritis, as well as those with certain viral infections, and patients who are transplant recipients or who have certain hematologic malignancies have been observed to have CD...
作者:... Mary B. Breslin , Kejing Song , Michael S. Lan
来源:[J].Cellular Signalling(IF 4.304), 2014, Vol.26 (4), pp.740-747Elsevier
摘要:Abstract(#br)INSM1 is an islet transcription factor essential for pancreas development. INSM1 functions as a transcriptional repressor of NeuroD / β2 and insulin gene in the pancreas. INSM1 also possesses extra-nuclear activities through binding to multiple cellular regulato...
作者:Kejing Song , Joyce B. Shepard ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2013, Vol.23 (7), pp.2197-2201Elsevier
摘要:Abstract(#br)The G-protein coupled receptor CXCR4 is a co-receptor for HIV-1 infection and is involved in signaling cell migration and proliferation. In a previous study of non-peptide, guanide-based CXCR4-binding compounds, spermine and spermidine phenylguanides inhibited H...

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