全部文献期刊会议图书|学者科研项目
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作者:... Teruyo Ito , Keiichi Hiramatsu , Kazuhisa Sekimizu
来源:[J].PLoS Pathogens(IF 9.127), 2017, Vol.7 (2)DOAJ
摘要:The F region downstream of the mecI gene in the SCCmec element in hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) contains two bidirectionally overlapping open reading frames (ORFs), the fudoh ORF and the psm-mec ORF. The psm-mec ORF encodes a cytol...
作者:... Tadashi Baba , Takashi Sasaki , Keiichi Hiramatsu
来源:[J].International Journal of Antimicrobial Agents(IF 4.415), 2015, Vol.46 (6), pp.666-673Elsevier
摘要:Abstract(#br)We previously reported the first ‘reverse antibiotic’ (RA), nybomycin (NYB), which showed a unique antimicrobial activity against Staphylococcus aureus strains. NYB specifically suppressed the growth of quinolone-resistant S. aureus strains but was not effective...
作者:Keiichi Hiramatsu , Yuki Katayama ...
来源:[J].International Journal of Medical Microbiology(IF 4.537), 2002, Vol.292 (2), pp.67-74Elsevier
摘要:Abstract(#br)A large and growing proportion of Staphylococcus aureus clinical isolates are methicillin resistant, and are resistant to practically all beta-lactam antibiotics. Methicillin-resistant S. aureus (MRSA) strains harbor mecA which is carried by a unique mobile genetic e...
作者:Keiichi Hiramatsu
来源:[J].The American Journal of Medicine(IF 4.768), 1998, Vol.104 (5), pp.7S-10SElsevier
摘要:Abstract(#br)Within the past year, infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains with reduced susceptibility to vancomycin (MIC = 8 μg/mL) have been reported in both Japan and the United States. The emergence of these strains poses a potenti...
作者:Keiichi Hiramatsu , Masayuki Igarashi ...
来源:[J].International Journal of Antimicrobial Agents(IF 4.415), 2012, Vol.39 (6), pp.478-485Elsevier
摘要:Abstract(#br)By screening cultures of soil bacteria, we re-discovered an old antibiotic (nybomycin) as an antibiotic with a novel feature. Nybomycin is active against quinolone-resistant Staphylococcus aureus strains with mutated gyrA genes but not against those with intact ...
作者:... Junichi Hatada , Keiichi Hiramatsu , Akihiko Kawana
来源:[J].AJIC: American Journal of Infection Control(IF 2.731), 2011, Vol.39 (10), pp.858-865Elsevier
摘要:Background(#br)Our retrospective investigation of methicillin-resistant Staphylococcus aureus (MRSA) infection at a hospital in Japan around 2007 suggested dissemination of community-associated MRSA (CA-MRSA) strains among healthy students in a Japanese boarding school, which fre...
作者:... Longzhu Cui , Keiichi Hiramatsu , Yuto Kamei
来源:[J].International Journal of Antimicrobial Agents(IF 4.415), 2003, Vol.22 (5), pp.545-547Elsevier
摘要:Abstract(#br)Antibacterial activity of 2,4-diacetylphloroglucinol (DAPG) was evaluated against 23 vancomycin-resistant Staphylococcus aureus (VRSA) strains isolated from several Asian and European countries, Brazil, South Africa and USA, and against vancomycin-resistant Enterococ...

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