全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Yukio Takamatsu , Kazuto Kobayashi , Kazutaka Ikeda
来源:[J].Molecular Brain(IF 4.202), 2017, Vol.10 (1)Springer
摘要:Dopamine is important for motor control and involved in the regulation of circadian rhythm. We previously found that dopamine-deficient (DD) mice became hyperactive in a novel environment 72 h after the last injection of L-3,4-dihydroxyphenylalanine (L-DOPA) when dopamine wa...
作者:... Kayo Nishizawa , Kazuto Kobayashi , Fumino Fujiyama
来源:[J].Brain Structure and Function(IF 7.837), 2017, Vol.222 (5), pp.2359-2378Springer
摘要:In the present study, we generated a novel parvalbumin (PV)-Cre rat model and conducted detailed morphological and electrophysiological investigations of axons from PV neurons in globus pallidus (GP). The GP is considered as a relay nucleus in the indirect pathway of the basal ga...
作者:Kazuto Kobayashi , Masahiko Watanabe ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (7)DOAJ
摘要:Narcolepsy patients often suffer from insomnia in addition to excessive daytime sleepiness. Narcoleptic animals also show behavioral instability characterized by frequent transitions between all vigilance states, exhibiting very short bouts of NREM sleep as well as wakefulness. T...
作者:... Shigeki Kato , Kazuto Kobayashi , Masamichi Sakagami
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (7)DOAJ
摘要:To precisely understand how higher cognitive functions are implemented in the prefrontal network of the brain, optogenetic and pharmacogenetic methods to manipulate the signal transmission of a specific neural pathway are required. The application of these methods, however, has b...
作者:Kazuto Kobayashi , Tsuyoshi Watanabe
来源:[J].Toxins(IF 2.129), 2014, Vol.6 (1), pp.254-269DOAJ
摘要:Methylglyoxal (MG), one of the uremic toxins, is a highly reactive alpha-dicarbonyl compound. Recent clinical studies have demonstrated the close associations of cognitive impairment (CI) with plasma MG levels and presence of kidney dysfunction. Therefore, the present study ...
作者:Kazuto Kobayashi , Akinori Nishi
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2016, Vol.66 (6), pp.435-446Springer
摘要:Abstract(#br)The authors have reviewed recent research advances in basal ganglia circuitry and function, as well as in related disorders from multidisciplinary perspectives derived from the results of morphological, electrophysiological, behavioral, biochemical and molecular biol...
作者:... Shigeki Kato , Kazuto Kobayashi , Masahiko Takada
来源:[J].Neuroscience Research(IF 2.204), 2017Elsevier
摘要:Abstract(#br)Lentiviral vectors have been used not only for various basic research experiments, but also for a wide range of gene therapy trials in animal models. The development of a pseudotyped lentiviral vector with the property of retrograde infection allows us to introduce f...
作者:Kazuto Kobayashi , Andreas Wree
来源:[J].Journal of Neuroscience Methods(IF 2.114), 2017, Vol.285, pp.49-57Elsevier
摘要:Abstract(#br)Background(#br)The nigrostriatal pathway is of great importance for the execution of movements, especially in the context of Parkinson’s disease. In research, analysis of this pathway often requires the application of severe animal experiments. Organotypic nigro...
作者:... Ryo Nagaoka , Kazuto Kobayashi , Yoshifumi Saijo
来源:[J].Ultrasonics(IF 2.028), 2018, Vol.84, pp.172-179Elsevier
摘要:Abstract(#br)Scanning acoustic microscopy (SAM) using impulsive signals is useful for characterization of biological tissues and cells. The operating center frequency of an ultrasonic device strongly depends on the performance characteristics of the device if the measurement is c...

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