全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Katarzyna Marta Zoltowska , Masato Maesako ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2017, Vol.12 (1)Springer
摘要:Alzheimer’s disease (AD)-linked protein, presenilin 1 (PS1), is present at the synapse, and the knock-out of presenilin in mice leads to synaptic dysfunction. On the other hand, synaptic activity was shown to influence PS1-dependent generation of distinct amyloid β (Aβ) spec...
作者:Katarzyna Marta Zoltowska , Masato Maesako ...
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-9DOAJ
摘要:Abstract Neuronal hyperactivity is one of the earliest events observed in Alzheimer’s disease (AD). Moreover, alterations in the expression of glutamate transporters have been reported to exacerbate amyloid pathology and cognitive deficits in transgenic AD mouse models. Howe...
作者:Katarzyna Marta Zoltowska , Katarzyna Laskowska-Kaszub ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2018, Vol.2018Hindawi
摘要:Alzheimer’s disease (AD) is the most common cause of dementia and a great socioeconomic burden in the aging society. Compelling evidence demonstrates that molecular change characteristics for AD, such as oxidative stress and amyloid β (A β ) oligomerization, precede by decad...
作者:Katarzyna Marta Zoltowska , Katarzyna Laskowska-Kaszub
来源:[J].Ageing Research Reviews(IF 5.953), 2018Elsevier
摘要:Abstract(#br)microRNAs (miRNAs) have been extensively studied as potential biomarkers for Alzheimer’s disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid (CSF) and brain tissue. However, due to the high variability between the reported data, stemmin...
作者:Katarzyna Marta Zoltowska , Natalie S Ryan ...
来源:[J].The EMBO Journal(IF 9.822), 2019, Vol.38 (12), pp.n/a-n/aWiley
摘要:Abstract(#br)γ‐Secretase complexes ( GSEC s) are multimeric membrane proteases involved in a variety of physiological processes and linked to Alzheimer's disease ( AD ). Presenilin ( PSEN , catalytic subunit), Nicastrin ( NCT ), Presenilin Enhancer 2 ( PEN ‐2), and Ante...

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