全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Kamila Borowczyk , Patrycja Olejarz ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2019, Vol.20 (13)DOAJ
摘要:(1) Antioxidants are involved in body protection mechanisms against reactive oxygen species. Amino acids such as glutathione (GSH) and N -acetylcysteine (NAC) are known to be involved in providing protection against oxidative lethality. A quick and simple method for the dete...
作者:Kamila Borowczyk , Justyna Stachniuk
来源:[J].Thrombosis Research(IF 3.133), 2015, Vol.136 (5), pp.911-916Elsevier
摘要:Abstract(#br)Background(#br)Recently, protein N-linked homocysteine (Hcy) has been measured in healthy subjects and patients with marked hyperhomocysteinemia. Since elevated total Hcy (tHcy) levels are associated with increased risk of venous thromboembolism (VTE), we aimed ...
作者:Kamila Borowczyk , Joanna Suliburska , Hieronim Jakubowski
来源:[J].Amino Acids(IF 3.914), 2018, Vol.50 (5), pp.537-546Springer
摘要:Abstract(#br)Growing human head hair contains a history of keratin and provides a unique model for studies of protein damage. Here, we examined mechanism of homocysteine (Hcy) accumulation and keratin damage in human hair. We found that the content of Hcy-keratin increased a...
作者:Kamila Borowczyk , Grażyna Chwatko ...
来源:[J].Talanta(IF 3.498), 2016, Vol.161, pp.917-924Elsevier
摘要:Abstract(#br)A fast and simple HPLC-based assay has been developed for the simultaneous determination of homocysteine (Hcy) and methionine (Met) in plasma and urine samples, utilizing as small volume of sample as 10 μL. The assay uses on-column derivatization with o -phthald...
作者:Kamila Borowczyk , Monika Wyszczelska-Rokiel ...
来源:[J].Journal of Chromatography B(IF 2.487), 2015, Vol.981-982, pp.57-64Elsevier
摘要:Abstract(#br)In this paper, we describe a simple and robust HPLC based method for determination of total low- and high-molecular-mass thiols, protein S-linked thiols and reduced albumin in plasma. The method is based on derivatization of analytes with 2-chloro-1-methylquinol...
作者:Kamila Borowczyk , Monika Wyszczelska-Rokiel ...
来源:[J].Journal of Chromatography B(IF 2.487), 2015, Vol.981-982, pp.57-64Elsevier
摘要:Abstract(#br)In this paper, we describe a simple and robust HPLC based method for determination of total low- and high-molecular-mass thiols, protein S-linked thiols and reduced albumin in plasma. The method is based on derivatization of analytes with 2-chloro-1-methylquinol...
作者:Kamila Borowczyk , Joanna Tisończyk , Hieronim Jakubowski
来源:[J].Amino Acids(IF 3.914), 2012, Vol.43 (3), pp.1339-1348Springer
摘要:Abstract(#br)Genetic or nutritional disorders in homocysteine (Hcy) metabolism elevate Hcy-thiolactone and cause heart and brain diseases. Hcy-thiolactone has been implicated in these diseases because it has the ability to modify protein lysine residues and generate toxic N ...
作者:Kamila Borowczyk , Jacek Wróblewski ...
来源:[J].International Journal of Genomics, 2018, Vol.2018DOAJ
摘要:Genetic or nutritional deficiencies in homocysteine (Hcy) metabolism increase Hcy-thiolactone, which causes protein damage by forming isopetide bonds with lysine residues, generating N-Hcy-protein. In the present work, we studied the prevalence and genetic determinants of ke...

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