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作者:Justin S. Lenhart , Monica C. Pillon ...
来源:[J].Research in Microbiology(IF 2.889), 2016, Vol.167 (1), pp.4-12Elsevier
摘要:Abstract(#br)DNA mismatch repair (MMR) is responsible for correcting errors formed during DNA replication. DNA polymerase errors include base mismatches and extra helical nucleotides referred to as insertion and deletion loops. In bacteria, MMR increases the fidelity of the chrom...
作者:Justin S. Lenhart , Anushi Sharma ...
来源:[J].Molecular Microbiology(IF 4.961), 2013, Vol.87 (3), pp.553-568Wiley
摘要:Summary(#br)Mismatch repair ( MMR ) increases the fidelity of DNA replication by identifying and correcting replication errors. Processivity clamps are vital components of DNA replication and MMR , yet the mechanism and extent to which they participate in MMR remains unclear...
作者:Justin S. Lenhart , Monica C. Pillon ...
来源:[J].Molecular Microbiology(IF 4.961), 2013, Vol.90 (4), pp.680-698Wiley
摘要:Summary(#br)During mismatch repair, MutS is responsible for mismatch detection and the recruitment of MutL to the mismatch through a mechanism that is unknown in most organisms. Here, we identified a discrete site on MutS that is occupied by MutL in B acillus subtilis . The ...
作者:Justin S. Lenhart , Jeremy W. Schroeder ...
来源:[J].Microbiology and Molecular Biology Reviews(IF 16.417), 2012, Vol.76 (3), pp.530-564Highwire
摘要:Summary: From microbes to multicellular eukaryotic organisms, all cells contain pathways responsible for genome maintenance. DNA replication allows for the faithful duplication of the genome, whereas DNA repair pathways preserve DNA integrity in response to damage originating fro...

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