全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Junji Ikeda , Masahiro Yoshitomi ...
来源:[J].Brain Tumor Pathology(IF 1.583), 2017, Vol.34 (4), pp.160-164Springer
摘要:Ependymomas are primary neuroepithelial malignancies that mainly occur during childhood, and arise from ependymal cells along the ventricular systems of the CNS. Recently, it was elucidated that two-thirds of supratentorial (ST) ependymomas harbor oncogenic fusions of RELA ,...
作者:Junji Ikeda , Lars Bauer
来源:[J].BMC Neurology(IF 2.564), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Achieving optimal symptom control with minimal side effects is a major goal in clinical practice. Dual-agent dopamine receptor agonist (DA) therapy in Parkinson’s disease (PD) may represent a promising approach to treatment, as the combination of...
作者:Junji Ikeda , Takayuki Tomida
来源:[J].Journal of Neurology(IF 3.578), 2014, Vol.261 (10), pp.1887-1893Springer
摘要:Abstract(#br)Rotigotine, a non-ergot dopamine receptor agonist, offers potential for continuous dopaminergic stimulation that could avoid the fluctuations observed with traditional treatments. We conducted a randomized, double-blind, placebo-controlled trial in Japanese pati...
作者:Junji Ikeda , Takayuki Tomida ...
来源:[J].Sleep Medicine(IF 3.487), 2015, Vol.16 (7), pp.871-876Elsevier
摘要:Abstract(#br)Objective(#br)To elucidate the prevalence and clinical characteristics of daytime restless legs syndrome (RLS) among patients with idiopathic RLS and investigate the effectiveness of rotigotine for daytime RLS.(#br)Methods(#br)In 256 enrolled RLS patients, we investi...
作者:... Takeuchi Masahiro , Junji Ikeda , Tomoo Funaki
来源:[J].European Journal of Drug Metabolism and Pharmacokinetics(IF 0.944), 2016, Vol.41 (4), pp.353-362Springer
摘要:Abstract(#br)Rotigotine is a dopamine receptor agonist indicated for the treatment of Parkinson’s disease and moderate-to-severe restless legs syndrome. Continuous transdermal delivery of rotigotine via a silicon-based patch maintains stable plasma concentrations over 24 h. ...
作者:... Jan-Peer Elshoff , Junji Ikeda , Tomoo Funaki
来源:[J].Clinical Drug Investigation(IF 1.915), 2014, Vol.34 (2), pp.95-105Springer
摘要:Abstract(#br) Background and Objectives(#br)Rotigotine is a dopamine receptor agonist with activity across the D 1 through to D 5 receptors as well as select serotonergic and adrenergic sites; continuous transdermal delivery of rotigotine with replacement of the patch once d...
作者:Junji Ikeda , Takayuki Tomida
来源:[J].Sleep Medicine(IF 3.487), 2013, Vol.14 (11), pp.1085-1091Elsevier
摘要:Abstract(#br)Objective(#br)We aimed to ascertain the efficacy and safety of transdermal rotigotine (2 and 3 mg/24 h) in Japanese patients with restless legs syndrome (RLS).(#br)Methods(#br)In our double-blind placebo-controlled study, 284 Japanese patients with idiopathic RL...

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