全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Julien Petrignet , Samuel Inack Ngi ...
来源:[J].Tetrahedron Letters(IF 2.397), 2014, Vol.55 (5), pp.982-984Elsevier
摘要:Abstract(#br)Total synthesis of (±)-herbaric acid and (±)-(4-methoxybenzyl)-5,7-dimethoxyphthalide, two natural phthalide products, was achieved in 8 steps and 5 steps, respectively, starting from commercially available 3,5-dimethoxyaniline. The key step of the sequence incl...
作者:... Mohamed Abarbri , Anne Silvestre , Julien Petrignet
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2016, Vol.26 (1), pp.114-120Elsevier
摘要:Abstract(#br)Screening of our chemical library to discover new molecules exhibiting in vitro activity against the invasion of host cells by Eimeria tenella revealed a lead compound with an IC 50 of 15 μM. Structure–activity relationship studies were conducted with 34 newly s...
作者:Julien Petrignet , Emilie Thiery ...
来源:[J].Synthesis(IF 2.5), 2014, pp.-Thieme
摘要:New and efficient methods for the synthesis of 7-substituted-4-trifluoromethylpyrimido[1,2-b]pyridazin-2-one derivatives using either two-step Suzuki/heterocyclization, or two-step heterocyclization/substitution sequences are developed. A variety of substituted products are obtai...
作者:Julien Petrignet , Thierry Roisnel , René Grée
来源:[J].Tetrahedron Letters(IF 2.397), 2006, Vol.47 (44), pp.7745-7748Elsevier
摘要:Abstract(#br)A new approach to functionalized 1,3 diols, such as 15 , is described using as the key step the tandem isomerization–aldolization reaction of allylic alcohols 1 . The chiral imidazolidine group is shown to play a key role for the stereocontrol during aldolizatio...
作者:Laurence Silpa , Julien Petrignet , Mohamed Abarbri
来源:[J].Synlett(IF 2.655), 2014, pp.-Thieme
摘要:A mild, simple method for the regioselective synthesis of thiadiazolo[3,2-a]pyrimidin-7-ones bearing a perfluoroalkyl group is reported. In order to study the core reactivity, various nucleophile substitutions were performed involving the reactive carbon–bromide bond via a o...
作者:Julien Petrignet , Romain Duwald ...
来源:[J].Advanced Synthesis & Catalysis(IF 5.535), 2013, Vol.355 (14鈥?5), pp.2936-2941Wiley
摘要:Abstract(#br)An original and convenient domino route to natural nostoclides I and II has been developed using a two‐step sequence consisting of a copper‐catalyzed tandem reaction associated with Suzuki cross‐coupling. The methodology employed for this total synthesis ap...
作者:Julien Petrignet , Hassan Halouchi ...
来源:[J].European Journal of Organic Chemistry(IF 3.344), 2012, Vol.2012 (31), pp.6212-6217Wiley
摘要:Abstract(#br)A new one‐pot domino process, involving four chemical transformations, for the synthesis of new dipyrido[1,2‐ a :3′,4′‐ d ]imidazole salts in a multicomponent reaction is reported. Various dipyrido[1,2‐ a :3′,4′‐ d ]imidazoles were obtained in mod...

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