全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Josiah R. Boivin , Tadafumi Hashimoto ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2017, Vol.12 (1)Springer
摘要:Amyloid-β oligomers (oAβ) are thought to mediate neurotoxicity in Alzheimer’s disease (AD), and previous studies in AD transgenic mice suggest that calcium dysregulation may contribute to these pathological effects. Even though AD mouse models remain a valuable resource to i...
作者:Josiah R. Boivin , A. Wren Thomas ...
来源:[J].Brain Research(IF 2.879), 2017, Vol.1654, pp.123-144Elsevier
摘要:Abstract(#br)Postnatal brain development is studded with sensitive periods during which experience dependent plasticity is enhanced. This enables rapid learning from environmental inputs and reorganization of cortical circuits that matches behavior with environmental contingencie...
作者:Josiah R. Boivin , Denise M. Piscopo , Linda Wilbrecht
来源:[J].Neuropharmacology(IF 4.114), 2015, Vol.97, pp.404-413Elsevier
摘要:Abstract(#br)Environmental stress and deprivation increase vulnerability to substance use disorders in humans and promote drug-seeking behavior in animal models. In contrast, experiences of mastery and stability may shape neural circuitry in ways that build resilience to future c...
作者:Josiah R. Boivin , Benjamin T. Saunders ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (4)PLOS
摘要:The neural basis of positive reinforcement is often studied in the laboratory using intracranial self-stimulation (ICSS), a simple behavioral model in which subjects perform an action in order to obtain exogenous stimulation of a specific brain area. Recently we showed that activ...

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