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作者:Jones H B
来源:[J].Kidney international(IF 7.916), 1998, Vol.53 (6), pp.1446-8
摘要:Hypertension is a common disorder that shows a polygenic mode of inheritance. Attempts to localize genes involved in the disorder have been carried out using both linkage and association tests. The relative merit of these two approaches is reviewed with an assessment of their uti...
作者:Jones H B
来源:[J].Genomics(IF 3.01), 1997, Vol.43 (3), pp.258-66
摘要:Radiation hybrid mapping has become an established tool for building physical maps. It represents a powerful way of constructing YAC contigs and high-resolution maps for positional cloning experiments. Ideally, radiation hybrids should not only provide support for the true order ...
作者:Jones H B , Eldridge S R ...
来源:[J].Regulatory toxicology and pharmacology : RTP(IF 2.132), 1996, Vol.23 (2), pp.117-27
摘要:The phenomena associated with nongenotoxic carcinogenesis are multifaceted and complex. Nongenotoxic carcinogens stimulate cell replication in the presence or the absence of cytotoxicity. Cell proliferation is pivotal in the neoplastic process, but the extent of its contribution ...
作者:Jones H B , Garside D A ...
来源:[J].Experimental and molecular pathology(IF 2.128), 1993, Vol.58 (3), pp.179-93
摘要:Phthalate esters are widely used in the manufacture of plastics and have been shown to cause testicular toxicity, purportedly, by targeting the Sertoli cell alone. Recent evidence, however, indicates that a paracrine control exists between Sertoli and Leydig cells and the breakdo...
作者:Jones H B
来源:[J].Toxicology(IF 4.017), 1988, Vol.49 (1), pp.3-15
摘要:The ways in which ultrastructural approaches have been applied to the investigation of xenobiotic-induced toxicity of the nervous system have been briefly reviewed. These approaches have been grouped in 3 broad areas, viz. morphology, function and composition. Firstly, morphologi...
作者:Jones H B , Cavanagh J B
来源:[J].Ultrastructural pathology(IF 0.978), 1984, Vol.6 (4), pp.359-62
作者:Jones H B , Gooneratne S R , Howell J M
来源:[J].Research in veterinary science(IF 1.774), 1984, Vol.37 (3), pp.273-82
摘要:The distribution of elements in the cells of the liver and kidney of normal sheep, of sheep chronically intoxicated with copper and in sheep given copper and thiomolybdate was studied by atomic absorption spectrophotometry, electron microscopy and electronprobe X-ray microanalysi...
作者:Jones H B , Reid D G , Luke J S
来源:[J].Toxicology in vitro : an international journal published in association with BIBRA(IF 2.65), 1989, Vol.3 (4), pp.299-309
摘要:SK&F 95018 is an antihypertensive compound with combined vasodilator and beta-adrenoceptor antagonist properties, which, when given to dogs by intravenous infusion, rapidly produced symptoms of intravascular haemolysis. The haemolytic potency of SK&F 95018 was confirmed in vitro ...
作者:Jones H B , Little S ...
来源:[J].Infection and immunity(IF 4.074), 2001, Vol.69 (1), pp.426-34
摘要:From a panel of nine inbred mice strains intranasally infected with Streptococcus pneumoniae type 2 strain, BALB/c mice were resistant and CBA/Ca and SJL mice were susceptible to infection. Further investigation revealed that BALB/c mice were able to prevent proliferation of pneu...

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